PMID- 36942879
OWN - NLM
STAT- MEDLINE
DCOM- 20231023
LR  - 20231023
IS  - 1784-973X (Electronic)
IS  - 0001-5385 (Linking)
VI  - 78
IP  - 8
DP  - 2023 Oct
TI  - A new marker for the prediction of contrast induced-acute kidney injury following 
      primary percutaneous coronary intervention: logarithm of haemoglobin-albumin 
      product.
PG  - 901-909
LID - 10.1080/00015385.2023.2187126 [doi]
AB  - BACKGROUND: Contrast-induced acute kidney injury (CI-AKI) is a disorder that 
      adversely affects the prognosis of STEMI. The study aimed to assess the 
      predictive value of a new marker, logarithm of haemoglobin and albumin product 
      (LHAP) on the risk of CI-AKI development after primary percutaneous coronary 
      intervention (p-pci). METHOD: We retrospectively enrolled 3057 patients with 
      ST-elevation acute myocardial infarction who were treated with p-PCI. The primary 
      outcome was CI-AKI, defined as >25% or >0.5 mg/dl increase of baseline creatinine 
      values during post-procedural 48 h. RESULTS: First, a baseline model was produced 
      to determine the predictors of CI-AKI, then haemoglobin, albumin and LHAP were 
      included in the base model and the performances of all models were compared. The 
      predictive accuracy (Likelihood ratio chi(2) and R(2)) and discrimination (ROC-AUC) 
      of the model including LHAP were significantly higher than that of models 
      including both albumin and Hgb. LHAP best cut-off value for the development of 
      CI-AKI was 9.26 (sensitivity 68% and specificity 66%). CONCLUSION: LHAP values 
      were the most important predictor of CI-AKI, followed by creatinine value and 
      Killip class. LHAP values are significantly associated with CI-AKI after p-PCI.
FAU - Ozveren, Olcay
AU  - Ozveren O
AD  - Department of Cardiology, Yeditepe University Hospital, Istanbul, Turkey.
FAU - Tanalp, Ali Cevat
AU  - Tanalp AC
AD  - Department of Cardiology, Gebze Medicalpark Hospital, Gebze, Turkey.
FAU - Tanboga, Ibrahim Halil
AU  - Tanboga IH
AD  - Department of Cardiology and Biostatistics, Nisantasi University, Istanbul, 
      Turkey.
FAU - Karagoz, Ali
AU  - Karagoz A
AUID- ORCID: 0000-0002-0438-2021
AD  - Department of Cardiology, Kartal Kosuyolu High Specialization Training and 
      Research Hospital, Istanbul, Turkey.
FAU - Saygi, Mehmet
AU  - Saygi M
AD  - Department of Cardiology, Hisar Intercontinental Hospital, Istanbul, Turkey.
FAU - Birdal, Oguzhan
AU  - Birdal O
AD  - Department of Cardiology, Ataturk University, Yakutiye, Turkey.
FAU - Turkyilmaz, Erdem
AU  - Turkyilmaz E
AD  - Department of Cardiology, Medifema Hospital, Torbali, Turkey.
FAU - Durmus, Erdal
AU  - Durmus E
AD  - Department of Cardiology, Yeditepe University Hospital, Istanbul, Turkey.
FAU - Oduncu, Vecih
AU  - Oduncu V
AD  - Department of Cardiology, Bahcesehir University, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20230321
PL  - England
TA  - Acta Cardiol
JT  - Acta cardiologica
JID - 0370570
RN  - 0 (Contrast Media)
RN  - AYI8EX34EU (Creatinine)
RN  - 0 (Hemoglobins)
RN  - 0 (Albumins)
SB  - IM
MH  - Humans
MH  - Risk Factors
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - Contrast Media/adverse effects
MH  - Creatinine/adverse effects
MH  - *Acute Kidney Injury/chemically induced/diagnosis
MH  - *ST Elevation Myocardial Infarction/diagnosis/surgery
MH  - Hemoglobins
MH  - Albumins/adverse effects
OTO - NOTNLM
OT  - Hemoglobin
OT  - acute kidney injury
OT  - albumin
OT  - creatinine
OT  - morbidity
OT  - myocardial infarction
EDAT- 2023/03/22 06:00
MHDA- 2023/10/23 12:44
CRDT- 2023/03/21 08:12
PHST- 2023/10/23 12:44 [medline]
PHST- 2023/03/22 06:00 [pubmed]
PHST- 2023/03/21 08:12 [entrez]
AID - 10.1080/00015385.2023.2187126 [doi]
PST - ppublish
SO  - Acta Cardiol. 2023 Oct;78(8):901-909. doi: 10.1080/00015385.2023.2187126. Epub 
      2023 Mar 21.