PMID- 36946172
OWN - NLM
STAT- MEDLINE
DCOM- 20230510
LR  - 20230513
IS  - 2222-1751 (Electronic)
IS  - 2222-1751 (Linking)
VI  - 12
IP  - 1
DP  - 2023 Dec
TI  - The role of dendritic cells in COVID-19 infection.
PG  - 2195019
LID - 10.1080/22221751.2023.2195019 [doi]
LID - 2195019
AB  - The persistent pandemic of coronavirus disease in 2019 (COVID-19) caused by 
      severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently poses a 
      major infectious threat to public health around the world. COVID-19 is an 
      infectious disease characterized by strong induction of inflammatory cytokines, 
      progressive lung inflammation, and potential multiple organs dysfunction. 
      SARS-CoV-2 infection is closely related to the innate immune system and adaptive 
      immune system. Dendritic cells (DCs), as a "bridge" connecting innate immunity 
      and adaptive immunity, play many important roles in viral diseases. In this 
      review, we will pay special attention to the possible mechanism of dendritic 
      cells in human viral transmission and clinical progression of diseases, as well 
      as the reduction and dysfunction of DCs in severe SARS-CoV-2 infection, so as to 
      understand the mechanism and immunological characteristics of SARS-CoV-2 
      infection.
FAU - Wang, Xuying
AU  - Wang X
AD  - Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, 
      Huazhong University of Science Technology, Wuhan, People's Republic of China.
AD  - Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of 
      Science and Technology, Wuhan, People's Republic of China.
FAU - Guan, Fei
AU  - Guan F
AD  - Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, 
      Huazhong University of Science Technology, Wuhan, People's Republic of China.
FAU - Miller, Heather
AU  - Miller H
AD  - Cytek Biosciences, R&D Clinical Reagents, Fremont, CA, USA.
FAU - Byazrova, Maria G
AU  - Byazrova MG
AD  - Laboratory of Immunochemistry, National Research Center Institute of Immunology, 
      Federal Medical Biological Agency of Russia, Moscow, Russia.
FAU - Cndotti, Fabio
AU  - Cndotti F
AD  - Division of Immunology and Allergy, Lausanne University Hospital and University 
      of Lausanne, Lausanne, Switzerland.
FAU - Benlagha, Kamel
AU  - Benlagha K
AD  - Institut de Recherche Saint-Louis, Universite de Paris, Paris, France.
FAU - Camara, Niels Olsen Saraiva
AU  - Camara NOS
AD  - Laboratory of Human Immunology, Department of Immunology, Institute of Biomedical 
      Sciences, University of Sao Paulo (USP), Sao Paulo, Brazil.
FAU - Lei, Jiahui
AU  - Lei J
AD  - Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, 
      Huazhong University of Science Technology, Wuhan, People's Republic of China.
FAU - Filatov, Alexander
AU  - Filatov A
AD  - Laboratory of Immunochemistry, National Research Center Institute of Immunology, 
      Federal Medical Biological Agency of Russia, Moscow, Russia.
FAU - Liu, Chaohong
AU  - Liu C
AD  - Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, 
      Huazhong University of Science Technology, Wuhan, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Emerg Microbes Infect
JT  - Emerging microbes & infections
JID - 101594885
RN  - 0 (Cytokines)
SB  - IM
MH  - Humans
MH  - *COVID-19
MH  - SARS-CoV-2
MH  - Cytokines
MH  - Immunity, Innate
MH  - Dendritic Cells
PMC - PMC10171120
OTO - NOTNLM
OT  - COVID-19
OT  - SARS-CoV-2
OT  - dendritic cell
OT  - immunopathology
OT  - viral infection
COIS- No potential conflict of interest was reported by the author(s).
EDAT- 2023/03/23 06:00
MHDA- 2023/05/10 06:42
PMCR- 2023/05/09
CRDT- 2023/03/22 04:52
PHST- 2023/05/10 06:42 [medline]
PHST- 2023/03/23 06:00 [pubmed]
PHST- 2023/03/22 04:52 [entrez]
PHST- 2023/05/09 00:00 [pmc-release]
AID - 2195019 [pii]
AID - 10.1080/22221751.2023.2195019 [doi]
PST - ppublish
SO  - Emerg Microbes Infect. 2023 Dec;12(1):2195019. doi: 
      10.1080/22221751.2023.2195019.