PMID- 36959899
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230325
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 16
DP  - 2023
TI  - Relationship Between Estimated Glucose Disposal Rate and Type 2 Diabetic 
      Retinopathy.
PG  - 807-818
LID - 10.2147/DMSO.S395818 [doi]
AB  - PURPOSE: To investigate the association between diabetic retinopathy (DR), DR 
      intensity, and estimated glucose disposal rate (eGDR) in individuals with 
      type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: This study comprised 1762 
      T2DM patients who were admitted between January and December, 2021. Overall, the 
      DR was identified in 430 patients. Based on the eGDR, the participants were 
      divided into four study groups. One-way analysis of variance was used to compare 
      the groups. The correlations between eGDR and DR risk, eGDR, and DR severity were 
      analyzed using regression analysis. Furthermore, these relationships were 
      analyzed in different sex groups. RESULTS: Patients with T2DM had a 19.75% 
      (348/1762) DR detection rate, whereas those with DR had a 22.41% (78/348) 
      proliferative DR detection rate. The DR group had substantially reduced levels of 
      eGDR compared with the non-DR group. Multivariate logistic regression analysis 
      demonstrated that reduced eGDR was an independent risk factor for DR, after 
      adjusting for confounding variables. eGDR correlated significantly with 
      proliferative DR in women but not in men. CONCLUSION: In Chinese individuals with 
      T2DM, lower eGDR was independently associated with a higher risk of DR.
CI  - (c) 2023 Meng et al.
FAU - Meng, Cuiqiao
AU  - Meng C
AD  - Health Examination Center, Hebei General Hospital, Shijiazhuang, People's 
      Republic of China.
FAU - Xing, Yuling
AU  - Xing Y
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, People's 
      Republic of China.
AD  - Graduate School of Hebei Medical University, Shijiazhuang, People's Republic of 
      China.
FAU - Huo, Lijing
AU  - Huo L
AD  - Department of Clinical Laboratory, Hebei General Hospital, Shijiazhuang, People's 
      Republic of China.
FAU - Ma, Huijuan
AU  - Ma H
AUID- ORCID: 0000-0002-4176-5013
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, People's 
      Republic of China.
AD  - Hebei Key Laboratory of Metabolic Diseases, Hebei General Hospital, Shijiazhuang, 
      Hebei, People's Republic of China.
AD  - Department of Internal Medicine, Hebei Medical University, Shijiazhuang, Hebei, 
      People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20230316
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC10028301
OTO - NOTNLM
OT  - diabetic retinopathy
OT  - estimated glucose disposal rate
OT  - type 2 diabetes mellitus
COIS- The authors declared no conflicts of interest.
EDAT- 2023/03/25 06:00
MHDA- 2023/03/25 06:01
PMCR- 2023/03/16
CRDT- 2023/03/24 02:16
PHST- 2022/11/19 00:00 [received]
PHST- 2023/03/08 00:00 [accepted]
PHST- 2023/03/24 02:16 [entrez]
PHST- 2023/03/25 06:00 [pubmed]
PHST- 2023/03/25 06:01 [medline]
PHST- 2023/03/16 00:00 [pmc-release]
AID - 395818 [pii]
AID - 10.2147/DMSO.S395818 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2023 Mar 16;16:807-818. doi: 10.2147/DMSO.S395818. 
      eCollection 2023.