PMID- 36966060 OWN - NLM STAT- MEDLINE DCOM- 20230619 LR - 20231206 IS - 2212-4411 (Electronic) VI - 136 IP - 1 DP - 2023 Jul TI - Radiomorphometric indices and fractal dimension of the mandible in individuals with osteogenesis imperfecta: a matched cross-sectional study. PG - 102-111 LID - S2212-4403(23)00030-5 [pii] LID - 10.1016/j.oooo.2023.02.002 [doi] AB - OBJECTIVE: The objective was to analyze radiomorphometric indices (RMIs) of mandibular cortical bone and fractal dimension (FD) of trabecular bone of individuals with osteogenesis imperfecta (OI) and compare the findings to those of individuals without OI. METHODS: Digital panoramic radiographs of 20 individuals with OI (case group) and 40 individuals without OI (control group) were examined. The RMIs of mandibular cortical index (MCI) and mandibular cortical thickness (MCT) were analyzed. FD of mandibular trabecular bone was calculated bilaterally in 3 regions. The chi-squared test and paired t test were used to compare the significance of differences between the groups. The effect size and minimal clinically important difference (MCID) were also determined. Significance was established at P < .05. RESULTS: Categories C2 and C3 of the MCI were more frequent in individuals with OI (P < .001). The Mean MCT was 2.08 +/- 0.79 in the OI case group and 2.91 +/- 0.60 in the control group (P < .001). Mean FD in the condylar region was significantly lower in the OI case group (P = .002). The effect size for these 2 measures was large, and the difference between groups was greater than the MCID. CONCLUSION: Radiographs of individuals with OI exhibited more porosity and diminished thickness of the mandibular cortical bone and lower FD values in the condylar trabecular bone. CI - Copyright (c) 2023 Elsevier Inc. All rights reserved. FAU - Prado, Heloisa Vieira AU - Prado HV AD - Department of Community and Preventive Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: heloisaprado92@hotmail.com. FAU - Debossan, Suelen Alves Teixeira AU - Debossan SAT AD - Department of Community and Preventive Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. FAU - Loayza, Katherine Silvana AU - Loayza KS AD - Department of Community and Preventive Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. FAU - Abreu, Lucas Guimaraes AU - Abreu LG AD - Department of Pediatric Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. FAU - Brasileiro, Claudia Borges AU - Brasileiro CB AD - Department of Oral Pathology and Surgery, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. FAU - Borges-Oliveira, Ana Cristina AU - Borges-Oliveira AC AD - Department of Community and Preventive Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230212 PL - United States TA - Oral Surg Oral Med Oral Pathol Oral Radiol JT - Oral surgery, oral medicine, oral pathology and oral radiology JID - 101576782 SB - IM MH - Humans MH - *Osteogenesis Imperfecta/diagnostic imaging MH - Cross-Sectional Studies MH - Bone Density MH - Fractals MH - Radiography, Panoramic/methods MH - Mandible/diagnostic imaging COIS- Declaration of interest None. EDAT- 2023/03/26 06:00 MHDA- 2023/06/19 13:08 CRDT- 2023/03/25 23:05 PHST- 2022/09/02 00:00 [received] PHST- 2023/01/25 00:00 [revised] PHST- 2023/02/04 00:00 [accepted] PHST- 2023/06/19 13:08 [medline] PHST- 2023/03/26 06:00 [pubmed] PHST- 2023/03/25 23:05 [entrez] AID - S2212-4403(23)00030-5 [pii] AID - 10.1016/j.oooo.2023.02.002 [doi] PST - ppublish SO - Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Jul;136(1):102-111. doi: 10.1016/j.oooo.2023.02.002. Epub 2023 Feb 12.