PMID- 36970333
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230328
IS  - 2297-055X (Print)
IS  - 2297-055X (Electronic)
IS  - 2297-055X (Linking)
VI  - 10
DP  - 2023
TI  - Quantitative evaluation of gastrocnemius medialis mass in patients with chronic 
      heart failure by gray-scale ultrasound and shear wave elastography.
PG  - 1132519
LID - 10.3389/fcvm.2023.1132519 [doi]
LID - 1132519
AB  - OBJECTIVE: To assess the usefulness of gray-scale ultrasound (US) and shear wave 
      elastography (SWE) in assessing the condition of the skeletal muscles in patients 
      with chronic heart failure (CHF). METHODS: We prospectively compared 20 patients 
      with clinically diagnosed CHF and a control population of 20 normal volunteers. 
      The gastrocnemius medialis (GM) of each individual in the rest and the 
      contraction position was assessed using gray-scale US and SWE. The quantitative 
      US parameters including the fascicle length (FL), pinnation angle (PA), echo 
      intensity (EI), and Young's modulus of the muscle were measured. RESULTS: In the 
      CHF group compared with the control group, in the rest position, there was a 
      significant difference in EI, PA, and FL of the GM (P < 0.001), but no 
      statistically significant difference in Young's modulus values (P > 0.05); 
      however, in the contraction position, all parameters were statistically different 
      between the two groups (P < 0.001). In the different subgroups of the CHF group 
      grouped according to New York Heart Association staging (NYHA) or left 
      ventricular ejection fraction (LVEF), there were no significant differences in 
      ultrasound parameters in the rest position. However, during the contraction of 
      GM, the smaller the FL and Young's modulus, the larger the PA and EI with the 
      increase of NYHA grade or the decrease of LVEF (P < 0.001). CONCLUSION: The 
      gray-scale US and SWE can provide an objective assessment of skeletal muscle 
      status for CHF patients and are expected to be used to guide their early 
      rehabilitation training and improve their prognosis.
CI  - (c) 2023 Yao, Zhang, Wu, Shu, Ye and Li.
FAU - Yao, Qiyu
AU  - Yao Q
AD  - Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Zhang, Yinglun
AU  - Zhang Y
AD  - Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Wu, Jun
AU  - Wu J
AD  - Department of Geriatric Cardiology, The First Affiliated Hospital of Nanjing 
      Medical University, Nanjing, China.
FAU - Shu, Hua
AU  - Shu H
AD  - Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Ye, Xinhua
AU  - Ye X
AD  - Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Li, Ao
AU  - Li A
AD  - Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
LA  - eng
PT  - Journal Article
DEP - 20230309
PL  - Switzerland
TA  - Front Cardiovasc Med
JT  - Frontiers in cardiovascular medicine
JID - 101653388
PMC - PMC10034337
OTO - NOTNLM
OT  - chronic heart failure
OT  - echo intensity
OT  - elastogarphy
OT  - muscle mass
OT  - ultrasound
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/03/28 06:00
MHDA- 2023/03/28 06:01
PMCR- 2023/01/01
CRDT- 2023/03/27 03:51
PHST- 2022/12/27 00:00 [received]
PHST- 2023/02/20 00:00 [accepted]
PHST- 2023/03/27 03:51 [entrez]
PHST- 2023/03/28 06:00 [pubmed]
PHST- 2023/03/28 06:01 [medline]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fcvm.2023.1132519 [doi]
PST - epublish
SO  - Front Cardiovasc Med. 2023 Mar 9;10:1132519. doi: 10.3389/fcvm.2023.1132519. 
      eCollection 2023.