PMID- 36970361
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230328
IS  - 2297-055X (Print)
IS  - 2297-055X (Electronic)
IS  - 2297-055X (Linking)
VI  - 10
DP  - 2023
TI  - Responsiveness and minimal clinically important difference of EQ-5D-5L in 
      patients with coronary heart disease after percutaneous coronary intervention: A 
      longitudinal study.
PG  - 1074969
LID - 10.3389/fcvm.2023.1074969 [doi]
LID - 1074969
AB  - BACKGROUND: Although the five-level version of the EuroQol five-dimensional 
      questionnaire (EQ-5D-5L) has been validated in various diseases, no empirical 
      study has evaluated the responsiveness and minimal clinically important 
      difference (MCID) of the instrument in patients with coronary heart disease 
      (CHD), which limits the interpretability and clinical application of EQ-5D-5L. 
      Therefore, this study aimed to determine the responsiveness and MCID of EQ-5D-5L 
      in patients with CHD who underwent percutaneous coronary intervention (PCI) and 
      identify the relationship between the MCID values and minimal detectable change 
      (MDC). METHODS: Patients with CHD were recruited for this longitudinal study at 
      the Tianjin Medical University's General Hospital in China. At baseline and 4 
      weeks after PCI, participants completed the EQ-5D-5L and Seattle Angina 
      Questionnaire (SAQ). Additionally, we used the effect size (ES) to assess the 
      responsiveness of EQ-5D-5L. The anchor-based, distribution-based, and 
      instrument-based methods were used in this study to calculate the MCID estimates. 
      The MCID estimates to MDC ratios were computed at the individual and group levels 
      at a 95% CI. RESULTS: Seventy-five patients with CHD completed the survey at both 
      baseline and follow-up. The EQ-5D-5L health state utility (HSU) improved by 0.125 
      at follow-up compared with baseline. The ES of EQ-5D HSU was 0.850 in all 
      patients and 1.152 in those who improved, indicating large responsiveness. The 
      average (range) MCID value of the EQ-5D-5L HSU was 0.071 (0.052-0.098). These 
      values can only be used to determine whether the change in scores were clinically 
      meaningful at the group level. CONCLUSION: EQ-5D-5L has large responsiveness 
      among CHD patients after undergoing PCI surgery. Future studies should focus on 
      calculating the responsiveness and MCID for deterioration and examining the 
      health changes at the individual level in CHD patients.
CI  - Copyright (c) 2023 Zheng, Dou, Fu and Li.
FAU - Zheng, Yu
AU  - Zheng Y
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
AD  - NHC Key Lab of Health Economics and Policy Research (Shandong University), Jinan, 
      Shandong, China.
AD  - Center for Health Preference Research, Shandong University, Jinan, Shandong, 
      China.
FAU - Dou, Lei
AU  - Dou L
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
AD  - NHC Key Lab of Health Economics and Policy Research (Shandong University), Jinan, 
      Shandong, China.
AD  - Center for Health Preference Research, Shandong University, Jinan, Shandong, 
      China.
FAU - Fu, Qiang
AU  - Fu Q
AD  - Department of Cardiovascular Surgery, General Hospital of Tianjin Medical 
      University, Tianjin, China.
FAU - Li, Shunping
AU  - Li S
AD  - Center for Health Management and Policy Research, School of Public Health, 
      Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
AD  - NHC Key Lab of Health Economics and Policy Research (Shandong University), Jinan, 
      Shandong, China.
AD  - Center for Health Preference Research, Shandong University, Jinan, Shandong, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20230309
PL  - Switzerland
TA  - Front Cardiovasc Med
JT  - Frontiers in cardiovascular medicine
JID - 101653388
PMC - PMC10034178
OTO - NOTNLM
OT  - EQ-5D-5L
OT  - coronary heart disease
OT  - minimal clinically important difference
OT  - minimal detectable change
OT  - percutaneous coronary intervention
OT  - responsiveness
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/03/28 06:00
MHDA- 2023/03/28 06:01
PMCR- 2023/03/09
CRDT- 2023/03/27 03:51
PHST- 2022/10/20 00:00 [received]
PHST- 2023/02/13 00:00 [accepted]
PHST- 2023/03/27 03:51 [entrez]
PHST- 2023/03/28 06:00 [pubmed]
PHST- 2023/03/28 06:01 [medline]
PHST- 2023/03/09 00:00 [pmc-release]
AID - 10.3389/fcvm.2023.1074969 [doi]
PST - epublish
SO  - Front Cardiovasc Med. 2023 Mar 9;10:1074969. doi: 10.3389/fcvm.2023.1074969. 
      eCollection 2023.