PMID- 36973922
OWN - NLM
STAT- MEDLINE
DCOM- 20230329
LR  - 20240317
IS  - 1760-4788 (Electronic)
IS  - 1279-7707 (Linking)
VI  - 27
IP  - 3
DP  - 2023
TI  - Trajectories of Intrinsic Capacity: Determinants and Associations with 
      Disability.
PG  - 174-181
LID - 10.1007/s12603-023-1881-5 [doi]
AB  - OBJECTIVES: Intrinsic capacity (IC) declines progressively with age, thereby 
      increasing the risk of disability. However, it is less known whether IC 
      trajectories are associated with disability. This study aims to identify the 
      different patterns of IC trajectories in older people, and examine their 
      determinants and associations with Instrumental Activities of Daily Living 
      (IADL). DESIGN: Cohort study. SETTING: Community centres in different regions in 
      Hong Kong. PARTICIPANTS AND MEASUREMENTS: Longitudinal data from 
      community-dwelling older people aged 60 years or above (n = 1371) collected 
      between 2016 and 2021 was analysed. Their mean age was 74.5 years, and 78.7% of 
      them were female. Repeated measurements of a set of 14 self-reported items were 
      used to generate IC scores at four time points using a bi-factor model. Latent 
      class growth analysis was performed to identify classes with distinct IC 
      trajectories. The association between class membership and IADL disability was 
      then examined using logistic regression. RESULTS: Three distinct IC trajectories 
      were identified. The 1st class included those with the highest level of baseline 
      IC and the least declining trajectory, whereas the 3rd class was composed by 
      those with the lowest level of baseline IC and the most declining trajectory. 
      Older age, female gender, lower perceived financial adequacy, living in public or 
      subsidized housing, and chronic diseases were associated with the 3rd class. 
      After adjusting for demographic factors, socioeconomic status, and the number of 
      chronic diseases, the 1st class was more likely to preserve IADL when compared 
      against the 2nd class, with OR being 3.179 (95% CI: 2.152-4.793), whereas for the 
      3rd class, the OR was 0.253 (95% CI: 0.178-0.359). CONCLUSION: Monitoring IC 
      trajectories is of relevance to clinical practice, as it helps shift the focus 
      from treating acute episodes of illness to preserving the functional ability of 
      older people.
FAU - Yu, R
AU  - Yu R
AD  - Ruby Yu, Department of Medicine and Therapeutics, Faculty of Medicine, The 
      Chinese University of Hong Kong, New Territories, Hong Kong, China, Tel: (852) 
      3943 5142, Fax: (852) 2637 9215, E-mail: rubyyu@cuhk.edu.hk.
FAU - Lai, D
AU  - Lai D
FAU - Leung, G
AU  - Leung G
FAU - Woo, J
AU  - Woo J
LA  - eng
PT  - Journal Article
PL  - France
TA  - J Nutr Health Aging
JT  - The journal of nutrition, health & aging
JID - 100893366
SB  - IM
CIN - J Nutr Health Aging. 2023;27(3):172-173. PMID: 36973921
MH  - Humans
MH  - Female
MH  - Aged
MH  - Male
MH  - *Activities of Daily Living
MH  - Cohort Studies
MH  - Independent Living
MH  - *Disabled Persons
MH  - Chronic Disease
OTO - NOTNLM
OT  - Determinants
OT  - disability
OT  - functional ability
OT  - healthy ageing
OT  - intrinsic capacity
OT  - trajectories
COIS- None declared.
EDAT- 2023/03/29 06:00
MHDA- 2023/03/29 06:05
CRDT- 2023/03/28 00:42
PHST- 2023/03/29 06:05 [medline]
PHST- 2023/03/28 00:42 [entrez]
PHST- 2023/03/29 06:00 [pubmed]
AID - S1279-7707(23)00301-9 [pii]
AID - 10.1007/s12603-023-1881-5 [doi]
PST - ppublish
SO  - J Nutr Health Aging. 2023;27(3):174-181. doi: 10.1007/s12603-023-1881-5.