PMID- 36976787
OWN - NLM
STAT- MEDLINE
DCOM- 20230802
LR  - 20230802
IS  - 1557-900X (Electronic)
IS  - 0892-7790 (Linking)
VI  - 37
IP  - 5
DP  - 2023 May
TI  - Long-Term Indwelling Tandem Polymeric Ureteral Stents for Benign Ureteral 
      Obstruction.
PG  - 516-520
LID - 10.1089/end.2022.0798 [doi]
AB  - Objective: To assess the outcome of tandem polymeric internal stents (TIS) for 
      benign ureteral obstruction (BUO). Material and Methods: We conducted a 
      retrospective study that included all consecutive patients treated for BUO by 
      means of TIS in a single tertiary center. Stents were replaced routinely every 12 
      months or earlier, when indicated. The primary outcome was permanent stent 
      failure, and the secondary outcomes included temporary failure, adverse events, 
      and renal function status. Kaplan-Meier and regression analyses were used to 
      estimate outcomes, and logistic regression was used to assess the association 
      between clinical variables and outcomes. Results: Between July 2007 and July 
      2021, 26 patients (34 renal units) underwent a total of 141 stent replacements, 
      with median follow-up of 2.6 years (interquartile range [IQR] 0.75-5). 
      Retroperitoneal fibrosis was the leading cause of TIS placement (46%). Permanent 
      failures occurred in 10 (29%) renal units, and the median time to permanent 
      failure was 728 days (IQR 242-1532). There was no association between 
      preoperative clinical variables and permanent failure. Temporary failure occurred 
      in four renal units (12%), which were treated by nephrostomy and eventually 
      returned to TIS. Urinary infection and kidney injury rates were one event for 
      every four and eight replacements, respectively. There was no significant 
      alteration in serum creatinine levels throughout the study (p = 0.18). 
      Conclusion: TIS provides long-term relief for patients with BUO and offers a safe 
      and effective solution for urinary diversion, while avoiding the need for 
      external tubes.
FAU - Veredgorn, Yotam
AU  - Veredgorn Y
AUID- ORCID: 0000-0003-2596-0916
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Savin, Ziv
AU  - Savin Z
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Herzberg, Haim
AU  - Herzberg H
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Masarwe, Ismael
AU  - Masarwe I
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Yossepowitch, Ofer
AU  - Yossepowitch O
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Sofer, Mario
AU  - Sofer M
AD  - Department of Urology, Tel Aviv Sourasky Medical Center, Affiliated to the 
      Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
LA  - eng
PT  - Journal Article
DEP - 20230328
PL  - United States
TA  - J Endourol
JT  - Journal of endourology
JID - 8807503
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - Middle Aged
MH  - Aged
MH  - *Ureteral Obstruction/surgery
MH  - *Ureter/surgery
MH  - *Stents
MH  - *Urinary Diversion
MH  - Retroperitoneal Fibrosis
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - BUO
OT  - benign ureteral obstruction
OT  - retroperitoneal fibrosis
OT  - stricture
OT  - tandem internal stents
EDAT- 2023/03/29 06:00
MHDA- 2023/05/18 06:42
CRDT- 2023/03/28 13:32
PHST- 2023/05/18 06:42 [medline]
PHST- 2023/03/29 06:00 [pubmed]
PHST- 2023/03/28 13:32 [entrez]
AID - 10.1089/end.2022.0798 [doi]
PST - ppublish
SO  - J Endourol. 2023 May;37(5):516-520. doi: 10.1089/end.2022.0798. Epub 2023 Mar 28.