PMID- 36990323
OWN - NLM
STAT- MEDLINE
DCOM- 20230807
LR  - 20240322
IS  - 1097-6825 (Electronic)
IS  - 0091-6749 (Print)
IS  - 0091-6749 (Linking)
VI  - 152
IP  - 2
DP  - 2023 Aug
TI  - Neighborhood environmental vulnerability and pediatric asthma morbidity in US 
      metropolitan areas.
PG  - 378-385.e2
LID - S0091-6749(23)00370-6 [pii]
LID - 10.1016/j.jaci.2023.03.018 [doi]
AB  - BACKGROUND: Research suggests demographic, economic, residential, and 
      health-related factors influence vulnerability to environmental exposures. 
      Greater environmental vulnerability may exacerbate environmentally related health 
      outcomes. We developed a neighborhood environmental vulnerability index (NEVI) to 
      operationalize environmental vulnerability on a neighborhood level. OBJECTIVE: We 
      explored the relationship between NEVI and pediatric asthma emergency department 
      (ED) visits (2014-19) in 3 US metropolitan areas: Los Angeles County, Calif; 
      Fulton County, Ga; and New York City, NY. METHODS: We performed separate linear 
      regression analyses examining the association between overall NEVI score and 
      domain-specific NEVI scores (demographic, economic, residential, health status) 
      with pediatric asthma ED visits (per 10,000) across each area. RESULTS: Linear 
      regression analyses suggest that higher overall and domain-specific NEVI scores 
      were associated with higher annual pediatric asthma ED visits. Adjusted R(2) 
      values suggest that overall NEVI scores explained at least 40% of the variance in 
      pediatric asthma ED visits. Overall NEVI scores explained more of the variance in 
      pediatric asthma ED visits in Fulton County. NEVI scores for the demographic, 
      economic, and health status domains explained more of the variance in pediatric 
      asthma ED visits in each area compared to the NEVI score for the residential 
      domain. CONCLUSION: Greater neighborhood environmental vulnerability was 
      associated with greater pediatric asthma ED visits in each area. The relationship 
      differed in effect size and variance explained across the areas. Future studies 
      can use NEVI to identify populations in need of greater resources to mitigate the 
      severity of environmentally related outcomes, such as pediatric asthma.
CI  - Copyright (c) 2023 American Academy of Allergy, Asthma & Immunology. Published by 
      Elsevier Inc. All rights reserved.
FAU - Kannoth, Sneha
AU  - Kannoth S
AD  - Department of Epidemiology, Mailman School of Public Health, Columbia University, 
      New York City, NY. Electronic address: sneha.kannoth@columbia.edu.
FAU - Chung, Sarah E
AU  - Chung SE
AD  - Department of Epidemiology, Mailman School of Public Health, Columbia University, 
      New York City, NY.
FAU - Tamakloe, Kelvin D
AU  - Tamakloe KD
AD  - Department of Epidemiology, Mailman School of Public Health, Columbia University, 
      New York City, NY.
FAU - Albrecht, Sandra S
AU  - Albrecht SS
AD  - Department of Epidemiology, Mailman School of Public Health, Columbia University, 
      New York City, NY.
FAU - Azan, Alexander
AU  - Azan A
AD  - Department of Population Health, New York University Langone Health, New York 
      City, NY.
FAU - Chambers, Earle C
AU  - Chambers EC
AD  - Department of Family and Social Medicine, Albert Einstein College of Medicine, 
      Bronx, NY.
FAU - Sheffield, Perry E
AU  - Sheffield PE
AD  - Department of Environmental Medicine and Public Health, Icahn School of Medicine 
      at Mount Sinai, New York City, NY.
FAU - Thompson, Azure
AU  - Thompson A
AD  - Department of Community Health Sciences, School of Public Health, SUNY Downstate 
      Health Sciences University, Brooklyn, NY.
FAU - Woo Baidal, Jennifer A
AU  - Woo Baidal JA
AD  - Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia 
      University, New York City, NY.
FAU - Lovinsky-Desir, Stephanie
AU  - Lovinsky-Desir S
AD  - Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia 
      University, New York City, NY.
FAU - Stingone, Jeanette A
AU  - Stingone JA
AD  - Department of Epidemiology, Mailman School of Public Health, Columbia University, 
      New York City, NY.
LA  - eng
GR  - R00 ES027022/ES/NIEHS NIH HHS/United States
GR  - UL1 TR001445/TR/NCATS NIH HHS/United States
GR  - K01 HL140216/HL/NHLBI NIH HHS/United States
GR  - P30 DK111022/DK/NIDDK NIH HHS/United States
GR  - P30 ES023515/ES/NIEHS NIH HHS/United States
GR  - K01 DK107791/DK/NIDDK NIH HHS/United States
GR  - R01 ES030717/ES/NIEHS NIH HHS/United States
GR  - P30 ES009089/ES/NIEHS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20230328
PL  - United States
TA  - J Allergy Clin Immunol
JT  - The Journal of allergy and clinical immunology
JID - 1275002
SB  - IM
MH  - Child
MH  - Humans
MH  - *Asthma/epidemiology
MH  - Morbidity
MH  - Emergency Service, Hospital
MH  - Residence Characteristics
MH  - *Nevus
PMC - PMC10524145
MID - NIHMS1886857
OTO - NOTNLM
OT  - Pediatric asthma
OT  - environmental vulnerability
OT  - neighborhood
OT  - racial disparities
COIS- Conflicts of Interest: All authors declare that they have no conflicts of 
      interest.
EDAT- 2023/03/30 06:00
MHDA- 2023/08/07 06:42
PMCR- 2024/08/01
CRDT- 2023/03/29 19:34
PHST- 2022/12/20 00:00 [received]
PHST- 2023/03/13 00:00 [revised]
PHST- 2023/03/17 00:00 [accepted]
PHST- 2024/08/01 00:00 [pmc-release]
PHST- 2023/08/07 06:42 [medline]
PHST- 2023/03/30 06:00 [pubmed]
PHST- 2023/03/29 19:34 [entrez]
AID - S0091-6749(23)00370-6 [pii]
AID - 10.1016/j.jaci.2023.03.018 [doi]
PST - ppublish
SO  - J Allergy Clin Immunol. 2023 Aug;152(2):378-385.e2. doi: 
      10.1016/j.jaci.2023.03.018. Epub 2023 Mar 28.