PMID- 36991233
OWN - NLM
STAT- MEDLINE
DCOM- 20230331
LR  - 20230410
IS  - 1436-5073 (Electronic)
IS  - 0026-3672 (Linking)
VI  - 190
IP  - 4
DP  - 2023 Mar 29
TI  - Synthesis of magnetic molecular imprinted polymer with a new functional monomer 
      for dispersive micro solid phase extraction of captopril from wastewater and 
      biological samples and determination by UV-Vis spectrophotometry.
PG  - 164
LID - 10.1007/s00604-023-05746-7 [doi]
AB  - A magnetic molecularly imprinted polymer (MMIP) was fabricated for captopril by 
      surface polymerization of Fe(3)O(4)@SiO(2) nanoparticles using a new functional 
      monomer of N-(allylcarbamothioyl)-2-chlorobenzamide. It was then employed as a 
      selective nanosorbent for dispersive magnetic micro solid phase extraction 
      (DM-mu-SPE) of captopril from biological and wastewater samples. To characterize 
      the physicochemical properties of the MMIP, different analytical methods such as 
      the vibrating sample magnetometer, field emission scanning electron microscopy, 
      Brunauer-Emmett-Teller, and Fourier transform infrared spectroscopy were 
      utilized. To gain the maximum extraction recovery of captopril, the influence of 
      various operating conditions was investigated and experimental 
      settings optimized. After the extraction step, the concentration of captopril was 
      measured by UV-Vis spectrophotometer at 245 nm. The assessments demonstrated that 
      the MMIP provides higher extraction efficiency in comparison to magnetic 
      non-imprinted polymer, suggesting the establishment of selective recognition 
      binding sites at the MMIP surface. The method depicted desirable figures of merit 
      of a low detection limit of 0.16 mug L(-1), a limit of quantification of 0.50 mug 
      L(-1), a linear dynamic range of 0.50-22.0 mug L(-1), and an acceptable 
      preconcentration factor of 333. The magnetic MIP was successfully employed for 
      preconcentration and extraction of trace amounts of captopril in real samples, 
      such as human blood serum, urine, and wastewater samples, with recoveries in the 
      range 95.7 to 102.6% and relative standard deviations < 5%.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, 
      part of Springer Nature.
FAU - Sabbaghi, Najmeh
AU  - Sabbaghi N
AD  - Department of Chemistry, Faculty of Science, Yazd University, 89195-741, Yazd, 
      Iran.
FAU - Haji Shabani, Ali Mohammad
AU  - Haji Shabani AM
AD  - Department of Chemistry, Faculty of Science, Yazd University, 89195-741, Yazd, 
      Iran. hshabani@yazd.ac.ir.
FAU - Dadfarnia, Shayessteh
AU  - Dadfarnia S
AUID- ORCID: 0000-0002-6191-0775
AD  - Department of Chemistry, Faculty of Science, Yazd University, 89195-741, Yazd, 
      Iran. sdadfarnia@yazd.ac.ir.
FAU - Farsadrooh, Majid
AU  - Farsadrooh M
AD  - Renewable Energies Research Laboratory, Department of Chemistry, Faculty of 
      Science, University of Sistan and Baluchestan, P.O. Box 98135 674, Zahedan, Iran.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230329
PL  - Austria
TA  - Mikrochim Acta
JT  - Mikrochimica acta
JID - 7808782
RN  - 9G64RSX1XD (Captopril)
RN  - 0 (Wastewater)
RN  - 0 (Polymers)
RN  - 7631-86-9 (Silicon Dioxide)
SB  - IM
MH  - Humans
MH  - *Captopril
MH  - *Wastewater
MH  - Polymers/chemistry
MH  - Silicon Dioxide
MH  - Solid Phase Extraction/methods
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Magnetic Phenomena
OTO - NOTNLM
OT  - Captopril
OT  - Dispersive magnetic micro solid phase extraction
OT  - Magnetic molecularly imprinted polymer
OT  - N-(allylcarbamothioyl)-2-chlorobenzamide
OT  - UV-Vis spectrophotometry
EDAT- 2023/03/30 06:00
MHDA- 2023/03/31 06:42
CRDT- 2023/03/29 23:26
PHST- 2022/12/17 00:00 [received]
PHST- 2023/03/10 00:00 [accepted]
PHST- 2023/03/31 06:42 [medline]
PHST- 2023/03/29 23:26 [entrez]
PHST- 2023/03/30 06:00 [pubmed]
AID - 10.1007/s00604-023-05746-7 [pii]
AID - 10.1007/s00604-023-05746-7 [doi]
PST - epublish
SO  - Mikrochim Acta. 2023 Mar 29;190(4):164. doi: 10.1007/s00604-023-05746-7.