PMID- 36991337 OWN - NLM STAT- MEDLINE DCOM- 20230331 LR - 20230410 IS - 1471-2261 (Electronic) IS - 1471-2261 (Linking) VI - 23 IP - 1 DP - 2023 Mar 29 TI - Chronic heart failure health-related quality of life questionnaire (CHFQOLQ-20): development and psychometric properties. PG - 165 LID - 10.1186/s12872-023-03197-9 [doi] LID - 165 AB - BACKGROUND: Health-related quality of life (HRQoL) is an important outcome indicator for chronic diseases. This study aimed to develop a new instrument for assessment of HRQoL in chronic heart failure (CHF) and evaluate its psychometric properties. METHODS: This study included two steps of conceptualization and item generation, and assessment of the psychometric properties of an instrument for measuring HRQoL in patients with CHF. A sample of 495 patients with confirmed diagnosis of heart failure participated in the study. In addition to content validity, exploratory and confirmatory factor analyses, concurrent validity, convergent validity, known groups comparison were performed to assess construct validity. Internal consistency, and stability were estimated by the Cronbach's alpha, the MacDonal's Omega, and intraclass correlation coefficients. RESULTS: The content validity of the developed chronic heart failure quality of life questionnaire was assessed by 10 experts. The exploratory factor analysis indicated a four-factor solution for the instrument containing 21 items that jointly accounted for 65.65% of variance observed. The confirmatory factor analysis confirmed the four factor solution with the following fit indexes (chi(2)/df = 2.214, CFI = 0.947, NFI = 0.91, TLI = 0.937, IFI = 0.947, GFI = 0.899, AGFI = 0.869, RMSEA = 0.063). However, at this stage one item was removed. The concurrent and convergent validity of the CHFQOLQ-20 were established using the Short Form Health Survey (SF-36), and the MacNew Heart Disease Quality of Life Questionnaire, respectively. The known-groups validity as assessed by using the New York Heart Association (NYHA) functional classification showed that the questionnaire discriminated well between patients who differed in functional classification. The internal consistency and test-retest reliability of the CHFQOLQ-20 were satisfactory, with a Cronbach's alpha and intraclass correlation coefficient (ICC) values of 0.93 and 0.84, respectively. CONCLUSION: The results confirmed that CHFQOLQ-20 is a valid and reliable instrument for measuring quality of life (QoL) in patients with CHF. It is a short and easy-to-use instrument that is also capable of assessing the cognitive functioning, which has been overlooked in previous questionnaires. CI - (c) 2023. The Author(s). FAU - Khajavi, Abdoljavad AU - Khajavi A AD - Department of Community Medicine, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran. FAU - Moshki, Mahdi AU - Moshki M AD - Department of Health Education and Health Promotion, School of Health, Gonabad University of Medical Sciences, Gonabad, Iran. drmoshki@gmail.com. AD - Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. drmoshki@gmail.com. FAU - Minaee, Shima AU - Minaee S AD - Department of Cardiovascular Diseases, Razavi Hospital, Mashhad, Iran. FAU - Vakilian, Farveh AU - Vakilian F AD - Department of Cardiology, Preventive Atherosclerotic Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. FAU - Montazeri, Ali AU - Montazeri A AD - Health Metrics Research Center, Iranian Institute for Health Sciences Research, ACECR, Tehran, Iran. AD - Faculty of Humanity Sciences, University of Sciences & Culture, Tehran, Iran. FAU - Hashemizadeh, Haydeh AU - Hashemizadeh H AD - Department of Nursing, Quchan Branch, Islamic Azad University, Quchan, Iran. haydeh_h_z@yahoo.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230329 PL - England TA - BMC Cardiovasc Disord JT - BMC cardiovascular disorders JID - 100968539 SB - IM MH - Humans MH - *Quality of Life/psychology MH - Psychometrics/methods MH - Reproducibility of Results MH - Surveys and Questionnaires MH - *Heart Failure/diagnosis MH - Chronic Disease MH - Factor Analysis, Statistical PMC - PMC10061999 OTO - NOTNLM OT - Chronic heart failure OT - Health-related quality of life OT - Iran OT - Patient-reported outcome measure OT - Reliability OT - Validity COIS- The authors declare that they have no competing interests. EDAT- 2023/03/30 06:00 MHDA- 2023/03/31 06:42 PMCR- 2023/03/29 CRDT- 2023/03/29 23:44 PHST- 2022/08/27 00:00 [received] PHST- 2023/03/22 00:00 [accepted] PHST- 2023/03/31 06:42 [medline] PHST- 2023/03/29 23:44 [entrez] PHST- 2023/03/30 06:00 [pubmed] PHST- 2023/03/29 00:00 [pmc-release] AID - 10.1186/s12872-023-03197-9 [pii] AID - 3197 [pii] AID - 10.1186/s12872-023-03197-9 [doi] PST - epublish SO - BMC Cardiovasc Disord. 2023 Mar 29;23(1):165. doi: 10.1186/s12872-023-03197-9.