PMID- 36997494 OWN - NLM STAT- MEDLINE DCOM- 20230403 LR - 20230403 IS - 1440-6047 (Electronic) IS - 0964-7058 (Linking) VI - 32 IP - 1 DP - 2023 TI - The relationship between dietary complexity and cognitive function in Guangxi, China: A cross-sectional study. PG - 133-148 LID - 10.6133/apjcn.202303_32(1).0017 [doi] AB - BACKGROUND AND OBJECTIVES: The composition of the human diet is complex and diverse, and the relation-ship between dietary composition and cognitive decline has not been adequately studied. Therefore, this study explored the possible association between food items and the risk of cognitive impairment. METHODS AND STUDY DESIGN: This cross-sectional study was based on an ecological longevity cohort and included 2881 participants (1086 men and 1795 women) aged >/=30 years between December 2018 and November 2019. The association between food items and the risk of cognitive impairment was explored using the Bayesian kernel machine regression (BKMR) learning model. RESULTS: Finally, 2881 participants (1086 men and 1795 women) were included. In all participants, the multivariable logistic analysis showed that fresh fruit consumption was associated with cognitive function (OR=0.999, 95% CI: 0.998-0.999, p=0.021). Using the BKMR model, none of the 18 food items were significantly correlated with cognitive function among women. In men, when the other food items were fixed at the 25th, 50th, and 75th percentile values (P25, estimate=-0.239; P50, estimate=-0.210; P75, estimate=-0.158), there was a negative correlation between fresh fruit consumption and the predicted risk of cognitive function disorders. CONCLUSIONS: Men displayed a negative association be-tween fresh fruit consumption and the risk of cognitive function disorders, but this was not apparent among women. FAU - Gou, Ruoyu AU - Gou R AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. Email: gouruoyu@stu.glmc.edu.cn. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Li, You AU - Li Y AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Cai, Jiansheng AU - Cai J AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Liu, Qiumei AU - Liu Q AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Pang, Weiyi AU - Pang W AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Luo, Tingyu AU - Luo T AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Xu, Min AU - Xu M AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Xiao, Song AU - Xiao S AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - He, Kailian AU - He K AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Li, Tingjun AU - Li T AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Li, Ruiying AU - Li R AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Xiao, Jie AU - Xiao J AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. FAU - Lin, Yinxia AU - Lin Y AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Lu, Yufu AU - Lu Y AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Qin, Jian AU - Qin J AD - Department of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Guangxi, PR China. FAU - Zhang, Zhiyong AU - Zhang Z AD - Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guangxi, PR China. Email: rpazz@glmc.edu.cn. AD - The Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Guilin Medical Uni-versity, Guangxi, PR China. LA - eng PT - Journal Article PL - China TA - Asia Pac J Clin Nutr JT - Asia Pacific journal of clinical nutrition JID - 9440304 SB - IM MH - Male MH - Humans MH - Female MH - Cross-Sectional Studies MH - Bayes Theorem MH - China/epidemiology MH - *Diet MH - *Cognition MH - Fruit EDAT- 2023/03/31 06:00 MHDA- 2023/04/03 06:41 CRDT- 2023/03/30 22:52 PHST- 2023/04/03 06:41 [medline] PHST- 2023/03/30 22:52 [entrez] PHST- 2023/03/31 06:00 [pubmed] AID - 10.6133/apjcn.202303_32(1).0017 [doi] PST - ppublish SO - Asia Pac J Clin Nutr. 2023;32(1):133-148. doi: 10.6133/apjcn.202303_32(1).0017.