PMID- 37000355
OWN - NLM
STAT- MEDLINE
DCOM- 20231229
LR  - 20231229
IS  - 1559-0291 (Electronic)
IS  - 0273-2289 (Linking)
VI  - 195
IP  - 12
DP  - 2023 Dec
TI  - Establishment of Sensitive Sandwich-Type Chemiluminescence Immunoassay for 
      Interleukin-18 in Urinary Samples.
PG  - 7414-7428
LID - 10.1007/s12010-023-04453-6 [doi]
AB  - Interleukin-18 (IL-18), a member of IL-1 cytokine superfamily, is deemed as an 
      important indicator of the kidney disease. Herein a sandwich chemiluminescence 
      immunoassay integrated with magnetic beads was conducted to detect IL-18 in 
      kidney disease. The detection limit and linear range were 0.0044 ng/mL and 
      0.01-2.7 ng/mL, respectively. Satisfactory recoveries were ranged from 91.70 to 
      101.18% with the relative standard deviation below 10%; interference bias of most 
      biomarkers were within allowable deviation range (+/- 15%). In summary, the whole 
      study was successfully applied to detect IL-18 levels in urine samples for 
      patients with kidney disease. The results showed that chemiluminescence 
      immunoassay for IL-18 detection could be used in the clinical application.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Fu, Xiaoling
AU  - Fu X
AD  - The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
FAU - Li, Lanya
AU  - Li L
AD  - Shuyang Hospital of Traditional Chinese Medicine, Suqian, 223600, China.
FAU - Wu, Guang
AU  - Wu G
AD  - Shuyang Hospital of Traditional Chinese Medicine, Suqian, 223600, China.
FAU - Tang, Kaike
AU  - Tang K
AD  - Hainan Cancer Hospital, Haikou, 570100, China.
FAU - Zhang, Jian
AU  - Zhang J
AD  - The Second People's Hospital of Hengshui, Hengshui, 053000, China.
FAU - Chen, Zhitian
AU  - Chen Z
AD  - Jiangsu MDK Biotech. Co. Ltd., Suqian, 223600, China.
FAU - Shi, Mingjin
AU  - Shi M
AD  - Jiangsu MDK Biotech. Co. Ltd., Suqian, 223600, China.
FAU - Zhang, Bo
AU  - Zhang B
AUID- ORCID: 0000-0002-2117-8217
AD  - Jiangsu MDK Biotech. Co. Ltd., Suqian, 223600, China. jsmdk520@163.com.
LA  - eng
GR  - 81860399/National Natural Science Foundation of China/
GR  - 20142BAB215072/Youth Science Foundation of Jiangxi Province/
GR  - 20202BBG72001/The Science and Technology Key R&D Program of Jiangxi Province/
PT  - Journal Article
DEP - 20230331
PL  - United States
TA  - Appl Biochem Biotechnol
JT  - Applied biochemistry and biotechnology
JID - 8208561
RN  - 0 (Interleukin-18)
RN  - 0 (Biomarkers)
SB  - IM
MH  - Humans
MH  - Immunoassay/methods
MH  - *Interleukin-18
MH  - Luminescence
MH  - Biomarkers
MH  - *Kidney Diseases
MH  - Luminescent Measurements/methods
OTO - NOTNLM
OT  - Biomarker
OT  - Chemiluminescence immunoassay
OT  - Interleukin-18
OT  - Kidney disease
EDAT- 2023/04/01 06:00
MHDA- 2023/12/29 06:43
CRDT- 2023/03/31 11:20
PHST- 2023/03/15 00:00 [accepted]
PHST- 2023/12/29 06:43 [medline]
PHST- 2023/04/01 06:00 [pubmed]
PHST- 2023/03/31 11:20 [entrez]
AID - 10.1007/s12010-023-04453-6 [pii]
AID - 10.1007/s12010-023-04453-6 [doi]
PST - ppublish
SO  - Appl Biochem Biotechnol. 2023 Dec;195(12):7414-7428. doi: 
      10.1007/s12010-023-04453-6. Epub 2023 Mar 31.