PMID- 37002750
OWN - NLM
STAT- MEDLINE
DCOM- 20230404
LR  - 20230404
IS  - 2408-8757 (Electronic)
IS  - 1022-4742 (Linking)
VI  - 32
IP  - 2
DP  - 2023 Apr
TI  - Prediction of Coronary Artery Disease Severity by Using CHA2DS2-VASC-HSF Score in 
      Patients with ST-Elevation Myocardial Infarction.
PG  - 393-402
AB  - CHADS(2) and CHA(2)DS(2)-VASc scores are widely used in clinical practice and include 
      similar risk factors for the development of coronary artery disease (CAD). It is 
      known that the factors comprising the newly defined CHA(2)DS(2)-VASC-HSF score 
      promote atherosclerosis and associated with severity of CAD. Objective of the 
      study was to find out the association of the CHA(2)DS(2)-VASC-HSF score with the 
      severity of CAD in patients with ST elevation myocardial infarction (STEMI). One 
      hundred (100) patients with STEMI were enrolled in this study after considering 
      inclusion and exclusion criteria over a one year period from October, 2017 to 
      September, 2018 in the Department of Cardiology, National Institute of 
      Cardiovascular Diseases, Dhaka, Bangladesh. Coronary angiogram was done within 
      index hospitalization and coronary artery disease severity was assessed by SYNTAX 
      score system. Patients were divided into two groups on the basis of SYNTAX score. 
      Patients with SYNTAX score >/=23 assigned as Group I and SYNTAX score <23 assigned 
      as Group II. The CHA(2)DS(2)-VASC-HSF score was calculated. Cut-off value of high 
      CHA(2)DS(2)-VASC-HSF score was >/=4.0. In this study mean age of study population was 
      51.8+/-9.8, male patients were predominant (79.0%). Among the studied patients, 
      highest percentage had history of smoking followed by hypertension, diabetes 
      mellitus and family history of CAD in Group I patients. It was found that DM and 
      family history of CAD and history of stroke/TIA were significantly higher in 
      Group I than Group II. An increasing trend of SYNTAX score was observed according 
      to the CHA(2)DS(2)-VASc-HSF score. SYNTAX score was significantly higher in 
      CHA2DS2-VASc-HSF score >/=4 than CHA(2)DS(2)-VASc-HSF score <4 (26.3+/-6.3 vs. 12.1+/-7.7, 
      p<0.001). Patients with CHA(2)DS(2)-VASC-HSF score >/=4 had severe coronary artery 
      disease than CHA(2)DS(2)-VASC-HSF score <4 assessed by SYNTAX score with 84.4% 
      sensitivity and 81.9% specificity (AUC:0.83, 95% CI: 0.746-0.915, p<0.001). 
      CHA(2)DS(2)-VASc-HSF score was positively correlated with the severity of CAD. This 
      score could be considered as a predictor of coronary artery disease severity.
FAU - Rahim, M A
AU  - Rahim MA
AD  - Dr Mohammad Abdur Rahim, MD, Department of Cardiology, National Institute of 
      Cardiovascular Diseases (NICVD), Dhaka, Bangladesh; E-mail: rahim1137@gmail.com.
FAU - Uddin, M J
AU  - Uddin MJ
FAU - Jahan, J
AU  - Jahan J
FAU - Chowdhury, T A
AU  - Chowdhury TA
FAU - Momen, A
AU  - Momen A
FAU - Islam, M M
AU  - Islam MM
FAU - Rahman, M A
AU  - Rahman MA
FAU - Bala, P
AU  - Bala P
FAU - Mamun, A
AU  - Mamun A
FAU - Chowdhury, F
AU  - Chowdhury F
FAU - Majumder, A R
AU  - Majumder AR
LA  - eng
PT  - Journal Article
PL  - Bangladesh
TA  - Mymensingh Med J
JT  - Mymensingh medical journal : MMJ
JID - 9601799
SB  - IM
MH  - Humans
MH  - Male
MH  - *Coronary Artery Disease/complications/epidemiology
MH  - *ST Elevation Myocardial Infarction
MH  - Risk Assessment
MH  - Prognosis
MH  - Bangladesh
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Retrospective Studies
EDAT- 2023/04/02 06:00
MHDA- 2023/04/04 06:42
CRDT- 2023/04/01 04:33
PHST- 2023/04/04 06:42 [medline]
PHST- 2023/04/01 04:33 [entrez]
PHST- 2023/04/02 06:00 [pubmed]
PST - ppublish
SO  - Mymensingh Med J. 2023 Apr;32(2):393-402.