PMID- 37009369 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230404 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 15 IP - 3 DP - 2023 Mar TI - Mid-Term Outlook Following Modified Senning's Operation for the Correction of Transposition of the Great Arteries: A Case Series and Review of Literature. PG - e36770 LID - 10.7759/cureus.36770 [doi] LID - e36770 AB - At the time of writing, two patients who underwent modified Senning's operation (MSO) for the treatment of transposition of great arteries (TGAs) were followed up. At the time of surgery, the patients were three months and 15 years old, respectively. The duration of the follow-up was three years, during which there was a good prognosis, and hence no further invasive treatments were required. There was normal functioning of the right ventricle (RV) in both patients, with the exception of a minor baffle leak in the three-month-old patient. At the annual three-year follow-up, the tricuspid regurgitation (systemic atrioventricular valve) status was moderate in the three-year-old child and mild in the 18-year-old girl. Both patients maintained sinus rhythm and are assigned classification as New York Heart Association (NYHA) Classes I and II. This study aims to assess the midterm outlook after MSO in order to identify and manage future long-term complications. Our report shows a positive outcome in terms of survival and functional activities among children with d-TGA; however, there is a strong need for future research to evaluate the prognosis in the long term (LT) and to assess the functioning of RV. CI - Copyright (c) 2023, Bhende et al. FAU - Bhende, Vishal V AU - Bhende VV AD - Pediatric Cardiac Surgery, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Sharma, Tanishq S AU - Sharma TS AD - Pediatric Cardiac Surgery, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. AD - Community Medicine, SAL Institute of Medical Sciences, Ahmedabad, IND. FAU - Subramaniam, Krishnan Ganapathy AU - Subramaniam KG AD - Pediatric Cardiac Surgery, Sri Padmavati Pediatric Heart Centre, Sri Venkateswara Institute of Medical Sciences (SVIMS) Campus, Tirupati, IND. FAU - Sharma, Ashwin S AU - Sharma AS AD - Internal Medicine, Gujarat Cancer Society Medical College, Hospital and Research Centre, Ahmedabad, IND. FAU - Kumar, Amit AU - Kumar A AD - Pediatric Cardiac Intensive Care, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Patel, Purvi R AU - Patel PR AD - Pediatrics, Pramukhswami Medical College & Shree Krishna Hospital, Bhaikaka University, Karamsad, IND. FAU - Panesar, Gurpreet AU - Panesar G AD - Cardiac Anaesthesiology, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Soni, Kunal A AU - Soni KA AD - Cardiac Anaesthesiology, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Dhami, Kartik B AU - Dhami KB AD - Cardiac Anaesthesiology, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Patel, Nirja P AU - Patel NP AD - Cardiac Anaesthesiology, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Majmudar, Hardil P AU - Majmudar HP AD - Pediatric Cardiac Surgery, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. FAU - Pathan, Sohilkhan R AU - Pathan SR AD - Clinical Research Services, Bhanubhai and Madhuben Patel Cardiac Centre, Bhaikaka University, Karamsad, IND. LA - eng PT - Case Reports DEP - 20230327 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC10053561 OTO - NOTNLM OT - cardiac surgical procedure OT - chd: congenital heart disease OT - myocardial protection OT - survival analysis OT - transposition COIS- The authors have declared that no competing interests exist. EDAT- 2023/04/04 06:00 MHDA- 2023/04/04 06:01 PMCR- 2023/03/27 CRDT- 2023/04/03 04:26 PHST- 2023/03/26 00:00 [accepted] PHST- 2023/04/04 06:01 [medline] PHST- 2023/04/03 04:26 [entrez] PHST- 2023/04/04 06:00 [pubmed] PHST- 2023/03/27 00:00 [pmc-release] AID - 10.7759/cureus.36770 [doi] PST - epublish SO - Cureus. 2023 Mar 27;15(3):e36770. doi: 10.7759/cureus.36770. eCollection 2023 Mar.