PMID- 37009379
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230404
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 3
DP  - 2023 Mar
TI  - Evaluation of Pulmonary Functions in Patients With Type 2 Diabetes Mellitus: A 
      Cross-Sectional Study.
PG  - e35628
LID - 10.7759/cureus.35628 [doi]
LID - e35628
AB  - Introduction Diabetes mellitus (DM) has been broadly recognized as the syndrome 
      of hyperglycemia leading to various macro- and microvascular complications. The 
      different physiological systems that have been identified as a target of these 
      injurious effects of hyperglycemia are the excretory system, ocular system, 
      central nervous system, and cardiovascular system. To date, not much focus has 
      been given to the respiratory system as a possible target for the deleterious 
      effect of hyperglycemia. Objective To assess the pulmonary functions in subjects 
      with type 2 diabetes mellitus (T2DM) and compare them with age and sex-matched 
      healthy controls. Methods This study was conducted on one hundred and twenty-five 
      patients with type 2 diabetes mellitus and a comparative number of age and 
      sex-matched non-diabetic individuals (control group) who met the inclusion and 
      exclusion criteria. RMS Helios 401 computerized spirometer was used to assess 
      pulmonary functions. Results The mean age of the control group and type 2 
      diabetics were 50.96+/-6.85 and 51.47+/-8.43 years, respectively. The results of the 
      present study showed significantly lower values of FVC, FEV1, FEF25-75%, and MVV 
      among diabetic subjects as compared to controls (<0.05). Conclusion We found that 
      pulmonary function parameters in diabetic subjects were consistently lower than 
      in healthy controls. This reduction in lung function is probably a chronic 
      complication of type 2 diabetes mellitus.
CI  - Copyright (c) 2023, Mittal et al.
FAU - Mittal, Swati
AU  - Mittal S
AD  - Physiology, All India Institute Of Medical Science, Deoghar, IND.
FAU - Jindal, Manisha
AU  - Jindal M
AD  - Physiology, School of Medical Sciences & Research, Sharda University, Greater 
      Noida, IND.
FAU - Srivastava, Saurabh
AU  - Srivastava S
AD  - Internal Medicine, Government Institute of Medical Science, Greater Noida, IND.
FAU - Sinha, Smriti
AU  - Sinha S
AD  - Physiology, Mamta Academy of Medical Sciences, Hyderabad, IND.
LA  - eng
PT  - Journal Article
DEP - 20230301
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10064250
OTO - NOTNLM
OT  - diabetes mellitus
OT  - forced expiratory volume in first second
OT  - forced vital capacity
OT  - pulmonary function test
OT  - restrictive pattern
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/04/04 06:00
MHDA- 2023/04/04 06:01
PMCR- 2023/03/01
CRDT- 2023/04/03 04:26
PHST- 2023/02/28 00:00 [accepted]
PHST- 2023/04/04 06:01 [medline]
PHST- 2023/04/03 04:26 [entrez]
PHST- 2023/04/04 06:00 [pubmed]
PHST- 2023/03/01 00:00 [pmc-release]
AID - 10.7759/cureus.35628 [doi]
PST - epublish
SO  - Cureus. 2023 Mar 1;15(3):e35628. doi: 10.7759/cureus.35628. eCollection 2023 Mar.