PMID- 37013072 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230405 IS - 2589-790X (Electronic) IS - 2589-790X (Linking) VI - 5 IP - 3 DP - 2023 Mar TI - Ambulatory Pulmonary Artery Pressure Monitoring Reduces Costs and Improves Outcomes in Symptomatic Heart Failure: A Single-Centre Canadian Experience. PG - 237-249 LID - 10.1016/j.cjco.2022.12.008 [doi] AB - BACKGROUND: Pulmonary artery pressure (PAP) monitoring reduces heart failure (HF) hospitalizations (HFHs) and improves quality of life in New York Heart Association (NYHA) class III HF. We evaluated the impact of PAP monitoring on outcomes and health spending in a Canadian ambulatory HF cohort. METHODS: Twenty NYHA III HF patients underwent wireless PAP implantation at Foothills Medical Centre, Calgary, Alberta. Baseline, and 3-, 6-, 9-, and 12-month assessments of laboratory parameters, hemodynamics, 6-minute walk text and Kansas City Cardiomyopathy Questionnaire scores were collected. Healthcare costs 1 year pre- and post-implantation were collected from administrative databases. RESULTS: Mean age was 70.6 years; 45% were female. Results were as follows: an 88% reduction in emergency room visits (P = 0.0009); an 87% reduction in HFHs (P < 0.0003); a 29% reduction in heart function clinic visits (P = 0.033), and a 178% increase in nurse calls (P < 0.0002). Questionnaire and 6-minute walk test scores at baseline vs last follow-up were 45.4 vs 48.4 (P = 0.48) and 364.4 vs 402.8 m (P = 0.58), respectively. Mean PAP at baseline vs follow-up was 31.5 vs 24.8 mm Hg (P = 0.005). NYHA class improved by at least one class in 85% of patients. Mean measurable HF-related spending preimplantation was CAD$29,814 per patient per year and postimplantation was CAD$25,642 per patient per year (including device cost). CONCLUSIONS: PAP monitoring demonstrated reductions in HFHs, and emergency room and heart function clinic visits, with improvements in NYHA class. Although further economic evaluation is needed, these results support the use of PAP monitoring as an effective and cost-neutral tool in HF management in appropriately selected patients in a publicly funded healthcare system. CI - (c) 2022 The Authors. FAU - Gibson, Jordan AU - Gibson J AD - Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada. FAU - McGrath, Kaitlin AU - McGrath K AD - Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada. FAU - Miller, Robert J H AU - Miller RJH AD - Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada. FAU - Sumner, Glen AU - Sumner G AD - Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada. FAU - Clarke, Brian AU - Clarke B AD - Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada. LA - eng PT - Journal Article DEP - 20221226 PL - United States TA - CJC Open JT - CJC open JID - 101763635 PMC - PMC10066443 EDAT- 2023/04/05 06:00 MHDA- 2023/04/05 06:01 PMCR- 2022/12/26 CRDT- 2023/04/04 01:59 PHST- 2022/09/07 00:00 [received] PHST- 2022/12/20 00:00 [accepted] PHST- 2023/04/05 06:01 [medline] PHST- 2023/04/04 01:59 [entrez] PHST- 2023/04/05 06:00 [pubmed] PHST- 2022/12/26 00:00 [pmc-release] AID - S2589-790X(22)00294-3 [pii] AID - 10.1016/j.cjco.2022.12.008 [doi] PST - epublish SO - CJC Open. 2022 Dec 26;5(3):237-249. doi: 10.1016/j.cjco.2022.12.008. eCollection 2023 Mar.