PMID- 37013765
OWN - NLM
STAT- MEDLINE
DCOM- 20230405
LR  - 20230503
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 27
IP  - 6
DP  - 2023 Mar
TI  - Predictive value of arm circumference (AC) and arm muscle circumference (AMC) 
      with cardiovascular risk in healthy and diabetic males.
PG  - 2477-2484
LID - 31781 [pii]
LID - 10.26355/eurrev_202303_31781 [doi]
AB  - OBJECTIVE: The predictive value of body simplified indices needs to be evaluated 
      properly for cardiovascular risk. This study aimed to assess and compare the 
      relative relationship of arm circumference (AC), arm muscle circumference (AMC), 
      body mass index (BMI), and waist-hip ratio (WHR) with Ultra-Sensitive C-Reactive 
      Protein (US-CRP) in healthy male subjects and with type 2 diabetes mellitus 
      (T2DM). PATIENTS AND METHODS: We performed the study at the department of 
      Physiology, College of Medicine & King Khalid University Hospital, King Saud 
      University, Riyadh, Saudi Arabia. It was a cross-sectional study with 93 healthy 
      male subjects and 112 type 2 diabetic male patients who underwent body 
      composition analysis by BIA and fasting venous blood samples were collected. 
      US-CRP and body composition were determined for all subjects. RESULTS: US-CRP is 
      correlated positively with AC (0.378) and BMI (0.394) more than AMC (0.282) and 
      WHR (0.253) which have lower correlation both in control and DM group. BCM has 
      the lowest correlation with US-CRP (0.105). The association between US-CRP and 
      AC, AMC, Body Fat Percent (BFP), and body fat mass (BFM) are statistically 
      significant except for BFP in DM group. In control group, AC is noticed to be a 
      better predictor for US-CRP, with area under curve (AUC) 64.2% (p=0.019), WHR 
      with AUC 72.6% (p<0.001), and BMI with AUC 65.4% (p=0.011) but AMC is not a good 
      predictor in control group with AUC 57.5% (p=0.213). In DM group, AC is noticed 
      to be a better predictor for US-CRP, with AUC 71.5% (p<0.001), WHR with AUC 67.4% 
      (p=0.004), BMI with AUC 70.9% (p=0.001), and AMC with AUC 65.2% (p=0.011). 
      CONCLUSIONS: Simplified muscle mass body indices like AC and AMC have significant 
      predictive value for assessing cardiovascular risk in both healthy population and 
      patients with T2DM. Therefore, AC could be used as a future predictor for 
      cardiovascular disease in healthy and DM patients. Further investigations are 
      needed to confirm its applicability.
FAU - Habib, S S
AU  - Habib SS
AD  - Department of Physiology, College of Medicine, King Saud University, Riyadh, 
      Saudi Arabia. shahidhabib44@hotmail.com.
FAU - Al-Khlaiwi, T
AU  - Al-Khlaiwi T
FAU - Habib, S M
AU  - Habib SM
FAU - Al-Khliwi, H
AU  - Al-Khliwi H
FAU - AbaAlkhail, M B
AU  - AbaAlkhail MB
FAU - Albuhayjan, N A
AU  - Albuhayjan NA
FAU - Aljawini, N
AU  - Aljawini N
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Humans
MH  - Male
MH  - *Diabetes Mellitus, Type 2
MH  - *Cardiovascular Diseases/diagnosis
MH  - Risk Factors
MH  - Arm
MH  - Cross-Sectional Studies
MH  - Waist-Hip Ratio
MH  - Body Mass Index
MH  - Heart Disease Risk Factors
MH  - C-Reactive Protein
MH  - Muscles
MH  - Waist Circumference
EDAT- 2023/04/05 06:00
MHDA- 2023/04/05 06:42
CRDT- 2023/04/04 04:33
PHST- 2023/04/05 06:42 [medline]
PHST- 2023/04/04 04:33 [entrez]
PHST- 2023/04/05 06:00 [pubmed]
AID - 31781 [pii]
AID - 10.26355/eurrev_202303_31781 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2023 Mar;27(6):2477-2484. doi: 
      10.26355/eurrev_202303_31781.