PMID- 37016652
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231102
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 3
DP  - 2023 Mar
TI  - Demographics and Characteristics of Acutely Decompensated Heart Failure (ADHF) 
      Patients in a Tertiary Care Center in Saudi Arabia.
PG  - e35724
LID - 10.7759/cureus.35724 [doi]
LID - e35724
AB  - BACKGROUND: Acute decompensated heart failure (ADHF) has been defined as the 
      gradual or rapid change in heart failure (HF) signs and symptoms resulting in a 
      need for urgent therapy. Patients with ADHF usually have multiple comorbidities 
      that contribute to the severity of exacerbation at admission, including diabetes 
      mellitus and chronic kidney disease. The prognosis for these individuals is 
      generally poor, with a high risk of readmission and death after discharge. 
      Unfortunately, there are limited studies in Saudi Arabia reporting the 
      characteristics of such patients. We aim to study the demographics and 
      characteristics of ADHF patients admitted to King Abdulaziz University Hospital 
      (KAUH) and analyze gender discrepancies and in-hospital mortality. METHODS: This 
      retrospective record review was conducted at KAUH. The study included 425 
      patients diagnosed with ADHF. The New York Heart Association (NYHA) 
      classification, underlying etiology of HF, comorbidities, left ventricular 
      ejection fraction (LVEF), vital signs, comprehensive metabolic panel at 
      admission, and in-hospital mortality were evaluated and analyzed. RESULTS: The 
      majority of the patients were males (52.5%), and the average age was 63 +/- 
      13.75 years. The most prevalent etiology of HF was hypertensive heart disease 
      (51.8%), followed by ischemic heart disease (42.8%). The most common comorbidity 
      was diabetes mellitus (73.6%), and the most common medication administered was 
      diuretics (95.5%). The mean LVEF was 37.9% +/- 16.0. In-hospital mortality occurred 
      in 10.4% of patients. The mean length of hospitalization was 16.7 +/- 86.2 days. 
      The mean blood urea nitrogen (BUN) (17.18 +/- 11.16) and creatinine (243.34 +/- 
      222.27) were higher in patients with in-hospital mortality. The mean difference 
      was statistically significant (P = 0.003 and P = 0.014). A higher length of 
      hospitalization was significantly associated with in-hospital mortality (P = 
      0.036). CONCLUSION: We found more than half of our sample to be males and 
      diabetes mellitus to be common among ADHF patients. Elevated BUN and creatinine 
      levels at the time of presentation, as well as patients who had been in the 
      hospital for a more extended period of time, were found to be associated with an 
      increased risk of in-hospital mortality.
CI  - Copyright (c) 2023, Alalawi et al.
FAU - Alalawi, Hassan
AU  - Alalawi H
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Fida, Hamza L
AU  - Fida HL
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Bokhary, Omar A
AU  - Bokhary OA
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Alhuzali, Majed A
AU  - Alhuzali MA
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Alharbi, Abdullah F
AU  - Alharbi AF
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Alhodian, Faisal Y
AU  - Alhodian FY
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Alsahari, Mohammed R
AU  - Alsahari MR
AD  - Medicine and Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
FAU - Siddiqui, Aisha M
AU  - Siddiqui AM
AD  - Internal Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
LA  - eng
PT  - Journal Article
DEP - 20230303
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10066922
OTO - NOTNLM
OT  - acute decompensated heart failure
OT  - adhf
OT  - ejection fraction
OT  - heart disease
OT  - heart failure
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/04/06 06:00
MHDA- 2023/04/06 06:01
PMCR- 2023/03/03
CRDT- 2023/04/05 01:44
PHST- 2023/03/03 00:00 [accepted]
PHST- 2023/04/06 06:01 [medline]
PHST- 2023/04/05 01:44 [entrez]
PHST- 2023/04/06 06:00 [pubmed]
PHST- 2023/03/03 00:00 [pmc-release]
AID - 10.7759/cureus.35724 [doi]
PST - epublish
SO  - Cureus. 2023 Mar 3;15(3):e35724. doi: 10.7759/cureus.35724. eCollection 2023 Mar.