PMID- 37016676
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230406
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 16
DP  - 2023
TI  - Associations of Colonoscopy and Risk of Hypoglycemia in Patients with Type 2 
      Diabetes.
PG  - 893-900
LID - 10.2147/DMSO.S401903 [doi]
AB  - PURPOSE: Inpatients undergoing colonoscopy may be at increased risk of 
      hypoglycemia. However, few high-quality studies have examined the relationship 
      between hypoglycemia and colonoscopy in patients with type 2 diabetes mellitus 
      (T2DM). PATIENTS AND METHODS: A total of 1016 patients from a large tertiary 
      hospital were enrolled in this retrospective study. We collected demographic 
      information, laboratory indices, colonoscopy information and hypoglycemia 
      information from the enrolled patients during hospitalization. Logistic 
      regression analysis was adopted to estimate the adjusted odds ratios to determine 
      the association between hypoglycemia and colonoscopy. RESULTS: Hypoglycemia 
      occurred in 80 of 788 (10.1%) patients without colonoscopy exposure and 37 of 228 
      (16.2%) patients with colonoscopy exposure. 25 patients (67.6%) had hypoglycemic 
      events from 3 hours to 68 hours after the end of colonoscopy. Adjusting for 
      demographic and clinical covariates, the risk of hypoglycemia was 1.99 times 
      higher in those who underwent colonoscopy than in those who did not (OR 1.99, 95% 
      CI 1.25-3.19). The association was consistent in subgroups of females, the 
      elderly, the overweight patients, patients with long duration of disease or 
      patients with suboptimal glycemic control. CONCLUSION: A strong association 
      between colonoscopy and an increased risk of hypoglycemia is observed in patients 
      with T2DM. When performing a colonoscopy for diabetics, the risk of hypoglycemia 
      should be considered even within 68 hours after colonoscopy.
CI  - (c) 2023 Yang et al.
FAU - Yang, Haiyan
AU  - Yang H
AUID- ORCID: 0000-0003-2270-7640
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, People's Republic of China.
FAU - Liu, Deliang
AU  - Liu D
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, People's Republic of China.
FAU - Zeng, Lin
AU  - Zeng L
AUID- ORCID: 0000-0001-6200-8815
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, People's Republic of China.
AD  - Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, 
      Shenzhen, People's Republic of China.
FAU - Peng, Siping
AU  - Peng S
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, People's Republic of China.
FAU - Liu, Huiling
AU  - Liu H
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20230329
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC10066886
OTO - NOTNLM
OT  - colonoscopy
OT  - fasting
OT  - hypoglycemia
OT  - retrospective study
OT  - type 2 diabetes mellitus
COIS- The authors report no conflicts of interest in this work.
EDAT- 2023/04/06 06:00
MHDA- 2023/04/06 06:01
PMCR- 2023/03/29
CRDT- 2023/04/05 01:45
PHST- 2022/12/29 00:00 [received]
PHST- 2023/03/27 00:00 [accepted]
PHST- 2023/04/06 06:01 [medline]
PHST- 2023/04/05 01:45 [entrez]
PHST- 2023/04/06 06:00 [pubmed]
PHST- 2023/03/29 00:00 [pmc-release]
AID - 401903 [pii]
AID - 10.2147/DMSO.S401903 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2023 Mar 29;16:893-900. doi: 10.2147/DMSO.S401903. 
      eCollection 2023.