PMID- 37018827
OWN - NLM
STAT- MEDLINE
DCOM- 20230703
LR  - 20231116
IS  - 1538-943X (Electronic)
IS  - 1058-2916 (Linking)
VI  - 69
IP  - 7
DP  - 2023 Jul 1
TI  - Prognosis of Venoarterial Extracorporeal Membrane Oxygenation in Mixed, 
      Cardiogenic and Septic Shock.
PG  - 658-664
LID - 10.1097/MAT.0000000000001933 [doi]
AB  - Mixed cardiogenic-septic shock (MS), defined as the combination of cardiogenic 
      (CS) and septic (SS) shock, is often encountered in cardiac intensive care units. 
      Herein, the authors compared the impact of venoarterial extracorporeal membrane 
      oxygenation (VA-ECMO) in MS, CS, and SS. Of 1,023 patients who received VA-ECMO 
      from January 2012 to February 2020 at a single center, 211 with pulmonary 
      embolism, hypovolemic shock, aortic dissection, and unknown causes of shock were 
      excluded. The remaining 812 patients were grouped based on the cause of shock at 
      VA-ECMO application: i) MS (n = 246, 30.3%), ii) CS (n = 466, 57.4%), iii) SS (n 
      = 100, 12.3%). The MS group was younger and had lower left ventricular ejection 
      fraction than the CS or SS group did. The 30 day and 1 year mortalities were the 
      highest in SS (30 day mortality: 50.4% vs. 43.3% vs. 69.0%, p < 0.001 for MS 
      versus CS versus SS, respectively; 1 year mortality: 67.5% vs. 53.2% vs. 81.0%, p 
      < 0.001 for MS versus CS versus SS, respectively). Posthoc analysis showed that 
      the 30 day mortality of MS was not different from CS, while the 1 year mortality 
      of MS was worse than CS but better than SS. Venoarterial extracorporeal membrane 
      oxygenation application for MS may help improve survival and should therefore be 
      considered if indicated.
CI  - Copyright (c) ASAIO 2023.
FAU - Kim, Ah-Ram
AU  - Kim AR
AUID- ORCID: 0000-0003-2489-948
AD  - From the Division of Cardiology, Department of Internal Medicine, Asan Medical 
      Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Hyun, Junho
AU  - Hyun J
AD  - From the Division of Cardiology, Department of Internal Medicine, Asan Medical 
      Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Lee, Sang Eun
AU  - Lee SE
AD  - From the Division of Cardiology, Department of Internal Medicine, Asan Medical 
      Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Hong, Jung Ae
AU  - Hong JA
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Kang, Pil-Je
AU  - Kang PJ
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Jung, Sung-Ho
AU  - Jung SH
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine, Seoul, Republic of Korea.
FAU - Kim, Min-Seok
AU  - Kim MS
AD  - From the Division of Cardiology, Department of Internal Medicine, Asan Medical 
      Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20230404
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
SB  - IM
MH  - Humans
MH  - *Extracorporeal Membrane Oxygenation/adverse effects
MH  - *Shock, Septic/therapy
MH  - Stroke Volume
MH  - Ventricular Function, Left
MH  - Prognosis
MH  - Shock, Cardiogenic
MH  - Retrospective Studies
COIS- Disclosure: The authors have no conflicts of interest to report.
EDAT- 2023/04/06 06:00
MHDA- 2023/07/03 06:41
CRDT- 2023/04/05 17:43
PHST- 2023/07/03 06:41 [medline]
PHST- 2023/04/06 06:00 [pubmed]
PHST- 2023/04/05 17:43 [entrez]
AID - 00002480-202307000-00005 [pii]
AID - 10.1097/MAT.0000000000001933 [doi]
PST - ppublish
SO  - ASAIO J. 2023 Jul 1;69(7):658-664. doi: 10.1097/MAT.0000000000001933. Epub 2023 
      Apr 4.