PMID- 37021283
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230407
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 14
DP  - 2023
TI  - Epidemiological features of traumatic spinal cord injury in China: A systematic 
      review and meta-analysis.
PG  - 1131791
LID - 10.3389/fneur.2023.1131791 [doi]
LID - 1131791
AB  - BACKGROUND: Traumatic spinal cord injury (TSCI) is a highly fatal and disabling 
      event, and its incidence rate is increasing in China. Therefore, we collated the 
      epidemiological factors of TSCI in different regions of China to update the 
      earlier systematic review published in 2018. METHOD: We searched four English and 
      three Chinese electronic databases from 1978 to October 1, 2022. From the 
      included reports, information on sample characteristics, incidence, injury 
      characteristics, prognostic factors, and economic burden was extracted. The 
      selection of data was based on the PRISMA statement. The quality of the included 
      studies was assessed by the Agency for Healthcare Research and Quality (AHRQ) 
      tool. The results of the meta-analysis were presented in the form of pooled 
      frequency and forest plots. RESULTS: A total of 59 reports (60 studies) from 23 
      provinces were included, of which 41 were in the Chinese language. The random 
      pooled incidence of TSCI in China was estimated to be 65.15 per million (95% CI: 
      47.20-83.10 per million), with a range of 6.7 to 569.7 per million. The pooled 
      male-to-female ratio was 1.95:1. The pooled mean age of the cases at the time of 
      injury was 45.4 years. Motor vehicle accidents (MVAs) and high falls were found 
      to be the leading causes of TSCI. Incomplete quadriplegia and AISA/Frankel grade 
      D were the most common types of TSCI. Cervical level injury was the most 
      prevalent. The pooled in-hospital mortality and complication rates for TSCI in 
      China were 3% (95% CI: 2-4%) and 35% (95% CI: 23-47%). Respiratory problems were 
      the most common complication and the leading cause of death. CONCLUSION: Compared 
      with previous studies, the epidemiological data on TSCI in China has changed 
      significantly. A need to update the data over time is essential to implement 
      appropriate preventive measures and formulate interventions according to the 
      characteristics of the Chinese population.
CI  - Copyright (c) 2023 Hu, Li, Hong, Xie, Li, Feng, Yang, Wang, Zhang, Yu and Fan.
FAU - Hu, Youpeng
AU  - Hu Y
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Li, Lianxin
AU  - Li L
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Hong, Binxue
AU  - Hong B
AD  - West China School of Medicine, West China Hospital, Sichuan University, Chengdu, 
      Sichuan, China.
FAU - Xie, Yizhou
AU  - Xie Y
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Li, Tong
AU  - Li T
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Feng, Chaoqun
AU  - Feng C
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Yang, Fei
AU  - Yang F
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Wang, Yehui
AU  - Wang Y
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Zhang, Jie
AU  - Zhang J
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Yu, Yang
AU  - Yu Y
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
FAU - Fan, Xiaohong
AU  - Fan X
AD  - The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 
      Chengdu, Sichuan, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230320
PL  - Switzerland
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC10069652
OTO - NOTNLM
OT  - China
OT  - epidemiological factors
OT  - incidence
OT  - systematic review and meta-analysis
OT  - traumatic spinal cord injury
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/04/07 06:00
MHDA- 2023/04/07 06:01
PMCR- 2023/03/20
CRDT- 2023/04/06 02:17
PHST- 2022/12/26 00:00 [received]
PHST- 2023/02/27 00:00 [accepted]
PHST- 2023/04/07 06:01 [medline]
PHST- 2023/04/06 02:17 [entrez]
PHST- 2023/04/07 06:00 [pubmed]
PHST- 2023/03/20 00:00 [pmc-release]
AID - 10.3389/fneur.2023.1131791 [doi]
PST - epublish
SO  - Front Neurol. 2023 Mar 20;14:1131791. doi: 10.3389/fneur.2023.1131791. 
      eCollection 2023.