PMID- 37023958 OWN - NLM STAT- MEDLINE DCOM- 20230731 LR - 20230731 IS - 1535-7732 (Electronic) IS - 1051-0443 (Linking) VI - 34 IP - 8 DP - 2023 Aug TI - Comparison between Suprapapillary and Transpapillary Uncovered Self-Expandable Metallic Stent Placement for Perihilar Cholangiocarcinoma. PG - 1400-1408 LID - S1051-0443(23)00265-8 [pii] LID - 10.1016/j.jvir.2023.03.031 [doi] AB - PURPOSE: To compare the effectiveness, adverse events (AEs), stent patency, and patient survival with suprapapillary and transpapillary uncovered self-expandable metallic stent placement for perihilar cholangiocarcinoma. MATERIALS AND METHODS: A single-center retrospective study of 54 patients with inoperable perihilar cholangiocarcinoma who underwent percutaneous transhepatic biliary stent placement between January 1, 2019, and August 31, 2021, was conducted. According to stent location, the patients were classified into 2 groups: suprapapillary (S) and transpapillary (T). Demographic data, Bismuth-Corlette classification, type and location of the stent, laboratory data, postprocedural AEs, procedural success, stent occlusion, reintervention rate, and mortality were compared between the groups. RESULTS: Stent placement was suprapapillary in 13 (24.1%) patients and transpapillary in 41 (75.9%) patients. Mean age was higher in Group T (78 vs 70.5 years; P = .046). Stent occlusion rates were similar in the 2 groups (Group S, 23.8%; Group T, 19.5%), as were AE rates, the most common being cholangitis (Group S, 23.1%; Group T, 24.4%). There were no significant differences in revision rate (Group S, 7.7%; Group T, 12.2%) and 30-day mortality rate (Group S, 15.4%; Group T, 19.5%). Ninety-day mortality rate was statistically significantly higher in Group T (46.3% vs 15.4%; P = .046). Preprocedural bilirubin level was higher in Group T, as were postprocedural leukocyte and C-reactive protein (CRP) levels. CONCLUSIONS: Suprapapillary and transpapillary stent placement procedures were similar in terms of procedural success, occlusion rate, revision rate, postprocedural AEs, and 30-day mortality. Ninety-day mortality rate and postprocedural leukocyte and CRP levels were higher in Group T, although these patients were also older and had higher preprocedural bilirubin levels. CI - Copyright (c) 2023 SIR. Published by Elsevier Inc. All rights reserved. FAU - Borges, Ana P AU - Borges AP AD - Department of Radiology, Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal. Electronic address: anapsborges0593@gmail.com. FAU - Silva, Antonio V AU - Silva AV AD - Faculty of Medicine, University of Coimbra, Coimbra, Portugal. FAU - Donato, Paulo AU - Donato P AD - Department of Radiology, Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal. LA - eng PT - Journal Article DEP - 20230405 PL - United States TA - J Vasc Interv Radiol JT - Journal of vascular and interventional radiology : JVIR JID - 9203369 RN - RFM9X3LJ49 (Bilirubin) SB - IM MH - Humans MH - Aged MH - *Klatskin Tumor/diagnostic imaging/therapy MH - Retrospective Studies MH - *Bile Duct Neoplasms/diagnostic imaging/therapy MH - Stents MH - Bilirubin MH - *Cholestasis MH - *Cholangiocarcinoma EDAT- 2023/04/07 06:00 MHDA- 2023/07/31 06:42 CRDT- 2023/04/06 19:26 PHST- 2022/09/24 00:00 [received] PHST- 2023/03/05 00:00 [revised] PHST- 2023/03/26 00:00 [accepted] PHST- 2023/07/31 06:42 [medline] PHST- 2023/04/07 06:00 [pubmed] PHST- 2023/04/06 19:26 [entrez] AID - S1051-0443(23)00265-8 [pii] AID - 10.1016/j.jvir.2023.03.031 [doi] PST - ppublish SO - J Vasc Interv Radiol. 2023 Aug;34(8):1400-1408. doi: 10.1016/j.jvir.2023.03.031. Epub 2023 Apr 5.