PMID- 37025755 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230411 IS - 2632-7899 (Electronic) IS - 2632-7899 (Linking) VI - 4 IP - 1 DP - 2023 Jan TI - Patient-Reported Outcome Measures in Clinical High Risk for Psychosis: A Systematic Review. PG - sgad006 LID - 10.1093/schizbullopen/sgad006 [doi] LID - sgad006 AB - A key issue in both research and clinical work with youth at clinical high risk (CHR) of psychosis is that there are clearly heterogenous clinical outcomes in addition to the development of psychosis. Thus, it is important to capture the psychopathologic outcomes of the CHR group and develop a core outcomes assessment set that may help in dissecting the heterogeneity and aid progress toward new treatments. In assessing psychopathology and often poor social and role functioning, we may be missing the important perspectives of the CHR individuals themselves. It is important to consider the perspectives of youth at CHR by using patient-reported outcome measures (PROMs). This systematic review of PROMs in CHR was conducted based on a comprehensive search of several databases and followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Sixty-four publications were included in the review examining PROMs for symptoms, functioning, quality of life, self-perceptions, stress, and resilience. Typically, PROMs were not the primary focus of the studies reviewed. The PROMs summarized here fit with results published elsewhere in the literature based on interviewer measures. However, very few of the measures used were validated for CHR or for youth. There are several recommendations for determining a core set of PROMs for use with CHR. CI - (c) The Author(s) 2023. Published by Oxford University Press on behalf of the University of Maryland's school of medicine, Maryland Psychiatric Research Center. FAU - Addington, Jean AU - Addington J AD - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. FAU - Chao, Amanda AU - Chao A AD - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. FAU - Braun, Amy AU - Braun A AD - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. FAU - Miller, Madeline AU - Miller M AD - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. FAU - Farris, Megan S AU - Farris MS AD - Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. LA - eng PT - Journal Article PT - Review DEP - 20230223 PL - United States TA - Schizophr Bull Open JT - Schizophrenia bulletin open JID - 101770329 PMC - PMC10069322 OTO - NOTNLM OT - clinical assessments OT - psychosis OT - self-report OT - ultra high risk EDAT- 2023/04/08 06:00 MHDA- 2023/04/08 06:01 PMCR- 2023/02/23 CRDT- 2023/04/07 02:34 PHST- 2023/04/08 06:01 [medline] PHST- 2023/04/07 02:34 [entrez] PHST- 2023/04/08 06:00 [pubmed] PHST- 2023/02/23 00:00 [pmc-release] AID - sgad006 [pii] AID - 10.1093/schizbullopen/sgad006 [doi] PST - epublish SO - Schizophr Bull Open. 2023 Feb 23;4(1):sgad006. doi: 10.1093/schizbullopen/sgad006. eCollection 2023 Jan.