PMID- 37030218
OWN - NLM
STAT- MEDLINE
DCOM- 20230501
LR  - 20230502
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 452
DP  - 2023 Jun 15
TI  - Fate and effects of graphene oxide alone and with sorbed benzo(a)pyrene in 
      mussels Mytilus galloprovincialis.
PG  - 131280
LID - S0304-3894(23)00562-9 [pii]
LID - 10.1016/j.jhazmat.2023.131280 [doi]
AB  - Graphene oxide (GO) has gained a great scientific and economic interest due to 
      its unique properties. As incorporation of GO in consumer products is rising, it 
      is expected that GO will end up in oceans. Due to its high surface to volume 
      ratio, GO can adsorb persistent organic pollutants (POPs), such as benzo(a)pyrene 
      (BaP), and act as carrier of POPs, increasing their bioavailability to marine 
      organisms. Thus, uptake and effects of GO in marine biota represent a major 
      concern. This work aimed to assess the potential hazards of GO, alone or with 
      sorbed BaP (GO+BaP), and BaP alone in marine mussels after 7 days of exposure. GO 
      was detected through Raman spectroscopy in the lumen of the digestive tract and 
      in feces of mussels exposed to GO and GO+BaP while BaP was bioaccumulated in 
      mussels exposed to GO+BaP, but especially in those exposed to BaP. Overall, GO 
      acted as a carrier of BaP to mussels but GO appeared to protect mussels towards 
      BaP accumulation. Some effects observed in mussels exposed to GO+BaP were due to 
      BaP carried onto GO nanoplatelets. Enhanced toxicity of GO+BaP with respect to GO 
      and/or BaP or to controls were identified for other biological responses, 
      demonstrating the complexity of interactions between GO and BaP.
CI  - Copyright (c) 2023 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Gonzalez-Soto, Nagore
AU  - Gonzalez-Soto N
AD  - CBET Research Group, Dept. Zoology and Animal Cell Biology, Science and 
      Technology Faculty and Plentzia Marine Station, University of the Basque Country 
      (UPV/EHU), Basque Country, Spain.
FAU - Blasco, Nagore
AU  - Blasco N
AD  - CBET Research Group, Dept. Zoology and Animal Cell Biology, Science and 
      Technology Faculty and Plentzia Marine Station, University of the Basque Country 
      (UPV/EHU), Basque Country, Spain.
FAU - Irazola, Mireia
AU  - Irazola M
AD  - Dept. Analytical Chemistry and Plentzia Marine Station, University of the Basque 
      Country (UPV/EHU), Basque Country, Spain.
FAU - Bilbao, Eider
AU  - Bilbao E
AD  - CBET Research Group, Dept. Zoology and Animal Cell Biology, Science and 
      Technology Faculty and Plentzia Marine Station, University of the Basque Country 
      (UPV/EHU), Basque Country, Spain.
FAU - Guilhermino, Lucia
AU  - Guilhermino L
AD  - Ecotoxicology Research Group, ICBAS, Institute of Biomedical Sciences of Abel 
      Salazar and Research Group of Ecotoxicology, Stress Ecology and Environmental 
      Health (ECOTOX), CIIMAR, Interdisciplinary Centre of Marine and Environmental 
      Research, University of Porto, Portugal.
FAU - Cajaraville, Miren P
AU  - Cajaraville MP
AD  - CBET Research Group, Dept. Zoology and Animal Cell Biology, Science and 
      Technology Faculty and Plentzia Marine Station, University of the Basque Country 
      (UPV/EHU), Basque Country, Spain. Electronic address: mirenp.cajaraville@ehu.eus.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230328
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
RN  - 3417WMA06D (Benzo(a)pyrene)
RN  - 0 (graphene oxide)
RN  - 0 (Water Pollutants, Chemical)
RN  - 7782-42-5 (Graphite)
SB  - IM
MH  - Animals
MH  - *Mytilus
MH  - Benzo(a)pyrene/toxicity/metabolism
MH  - *Water Pollutants, Chemical/analysis
MH  - *Graphite/toxicity
OTO - NOTNLM
OT  - Biological responses
OT  - Bivalve mollusks
OT  - Graphene family nanomaterials
OT  - Polycyclic aromatic hydrocarbons
OT  - Trojan Horse effect
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/04/09 06:00
MHDA- 2023/05/01 06:41
CRDT- 2023/04/08 18:09
PHST- 2022/11/09 00:00 [received]
PHST- 2023/03/13 00:00 [revised]
PHST- 2023/03/22 00:00 [accepted]
PHST- 2023/05/01 06:41 [medline]
PHST- 2023/04/09 06:00 [pubmed]
PHST- 2023/04/08 18:09 [entrez]
AID - S0304-3894(23)00562-9 [pii]
AID - 10.1016/j.jhazmat.2023.131280 [doi]
PST - ppublish
SO  - J Hazard Mater. 2023 Jun 15;452:131280. doi: 10.1016/j.jhazmat.2023.131280. Epub 
      2023 Mar 28.