PMID- 37034368
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230411
IS  - 2529-198X (Electronic)
IS  - 2529-198X (Linking)
VI  - 33
IP  - 4
DP  - 2022 Dec
TI  - Takayasu Arteritis is Associated with Impaired Arterial Stiffness: A 
      Meta-Analysis of Observational Studies.
PG  - 387-392
LID - 10.31138/mjr.33.4.387 [doi]
AB  - INTRODUCTION/OBJECTIVE: Takayasu arteritis, a large vessel vasculitis, is 
      strongly associated with increased risk for cardiovascular and chronic kidney 
      disease. Arterial stiffness represents an established prognostic marker of 
      cardiovascular disease development in the general population. A few studies have 
      assessed the effect of Takayasu arteritis on arterial stiffness indices. Herein, 
      we sought to provide pooled effect estimates regarding the impact of Takayasu 
      arteritis on arterial stiffness, by retrieving relevant, available observational 
      studies. METHODS: On 1(st) May, 2022, we searched two major electronic databases 
      and grey literature sources for relevant observational studies. We set as primary 
      outcome the mean difference in carotid femoral PWV (cfPWV) between patients with 
      Takayasu arteritis compared to controls. RESULTS: Regarding the primary outcome, 
      we pooled data from 3 studies in a total of 125 enrolled subjects, demonstrating 
      that Takayasu arteritis is associated with a significant increase in cfPWV by 
      2.06 m/s (MD = 2.06, 95% CI; 1.29 - 2.83, I(2) = 0%, p < 0.001), compared to 
      controls. CONCLUSION: The present preliminary meta-analysis demonstrates the 
      potential deleterious effects of Takayasu arteritis on arterial stiffness. 
      Prognostic implications must be confirmed in larger, prospective studies.
CI  - (c) 2022 The Mediterranean Journal of Rheumatology (MJR).
FAU - Patoulias, Dimitrios
AU  - Patoulias D
AD  - Second Propaedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, General Hospital "Hippokration", Thessaloniki, Greece.
FAU - Dimosiari, Athina
AU  - Dimosiari A
AD  - Department of Internal Medicine, Interbalkan Medical Center, Thessaloniki, 
      Greece.
FAU - Michailidis, Theodoros
AU  - Michailidis T
AD  - Second Department of Internal Medicine, Aristotle University of Thessaloniki, 
      General Hospital "Hippokration", Thessaloniki, Greece.
LA  - eng
PT  - Journal Article
DEP - 20221231
PL  - Greece
TA  - Mediterr J Rheumatol
JT  - Mediterranean journal of rheumatology
JID - 101730166
PMC - PMC10075371
OTO - NOTNLM
OT  - Takayasu arteritis
OT  - arterial stiffness
OT  - cardiovascular disease
COIS- All authors confirm no financial or personal relationship with a third party 
      whose interests could be positively or negatively influenced by the article's 
      content.
EDAT- 2023/04/11 06:00
MHDA- 2023/04/11 06:01
PMCR- 2022/12/31
CRDT- 2023/04/10 04:06
PHST- 2022/05/26 00:00 [received]
PHST- 2022/08/07 00:00 [revised]
PHST- 2022/08/24 00:00 [accepted]
PHST- 2023/04/11 06:01 [medline]
PHST- 2023/04/10 04:06 [entrez]
PHST- 2023/04/11 06:00 [pubmed]
PHST- 2022/12/31 00:00 [pmc-release]
AID - MJR-33-4-387 [pii]
AID - 10.31138/mjr.33.4.387 [doi]
PST - epublish
SO  - Mediterr J Rheumatol. 2022 Dec 31;33(4):387-392. doi: 10.31138/mjr.33.4.387. 
      eCollection 2022 Dec.