PMID- 37037911
OWN - NLM
STAT- MEDLINE
DCOM- 20230517
LR  - 20230517
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 415
IP  - 14
DP  - 2023 Jun
TI  - Improved analysis of folpet and captan in foods using liquid 
      chromatography-triple quadrupole linear ion trap mass spectrometry: applying mass 
      filtering, collision, and trapping conditions.
PG  - 2693-2703
LID - 10.1007/s00216-023-04667-x [doi]
AB  - Accurate and highly sensitive analysis of folpet and captan was accomplished 
      using liquid chromatography-triple quadrupole linear ion trap mass spectrometry 
      (LC-QqQIT) with selective ion mode; mass filtering, collision, and trapping 
      condition. Dimensional mass spectrometry (MS(3)) parameters were optimized for 
      the residue detection of folpet and captan in six food commodities (apples, 
      tomatoes, sweet pepper, wheat flour, sesame seeds, and fennel seeds). The sample 
      preparation method was based on the known QuEChERS protocol, except a mixture of 
      acetonitrile/acetone was used for the sample extraction from the sesame seeds. 
      The robustness and reliability of the developed MS(3) method were demonstrated by 
      performing a full validation, according to SANTE/11312/2021, at 0.01-0.25 mg/kg. 
      Recovery ranged from 83 to 118% with a relative standard deviation below 19% in 
      all the tested commodities, and limits of quantifications (LOQs) were 0.01 mg/kg 
      in apples and tomatoes; 0.03 mg/kg in sweet pepper; and 0.05 mg/kg in wheat 
      flour, sesame seeds, and fennel seeds. Monitoring results showed that about 90% 
      of apples contained captan residue, and in sweet pepper, concentrations of captan 
      and folpet as high as 1.57 and 0.97 mg/kg were found, respectively. The novel 
      developed MS(3) method enabled more reliable identification of these commonly 
      problematic fungicides at lower LOQs than previously reported methods.
CI  - (c) 2023. Springer-Verlag GmbH Germany, part of Springer Nature.
FAU - El-Sheikh, Abd-Allah A
AU  - El-Sheikh AA
AD  - Agricultural Research Center, Central Laboratory of Residue Analysis of 
      Pesticides and Heavy Metals in Foods, Dokki, P.O. Box 12311, Giza, Egypt.
AD  - Environment and Bio-Agriculture Department, Faculty of Agriculture, Al-Azhar 
      University, P.O. Box 11884, Cairo, Egypt.
FAU - Elhamalawy, Osama H
AU  - Elhamalawy OH
AD  - Environment and Bio-Agriculture Department, Faculty of Agriculture, Al-Azhar 
      University, P.O. Box 11884, Cairo, Egypt.
FAU - Taha, Sherif M
AU  - Taha SM
AUID- ORCID: 0000-0001-7232-9911
AD  - Agricultural Research Center, Central Laboratory of Residue Analysis of 
      Pesticides and Heavy Metals in Foods, Dokki, P.O. Box 12311, Giza, Egypt. 
      sherif2taha@gmail.com.
FAU - Eissa, Fawzy I
AU  - Eissa FI
AD  - Environment and Bio-Agriculture Department, Faculty of Agriculture, Al-Azhar 
      University, P.O. Box 11884, Cairo, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20230411
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - EOL5G26Q9F (Captan)
RN  - X5NFK36917 (folpet)
SB  - IM
MH  - *Captan
MH  - Flour/analysis
MH  - Reproducibility of Results
MH  - Triticum
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Chromatography, Liquid/methods
MH  - *Malus/chemistry
MH  - Chromatography, High Pressure Liquid
OTO - NOTNLM
OT  - Captan
OT  - Folpet
OT  - LC-QqQIT
OT  - Linear ion trap
OT  - MS3
OT  - QuEChERS
EDAT- 2023/04/11 06:00
MHDA- 2023/05/17 06:42
CRDT- 2023/04/10 23:19
PHST- 2023/01/17 00:00 [received]
PHST- 2023/03/21 00:00 [accepted]
PHST- 2023/03/17 00:00 [revised]
PHST- 2023/05/17 06:42 [medline]
PHST- 2023/04/11 06:00 [pubmed]
PHST- 2023/04/10 23:19 [entrez]
AID - 10.1007/s00216-023-04667-x [pii]
AID - 10.1007/s00216-023-04667-x [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2023 Jun;415(14):2693-2703. doi: 10.1007/s00216-023-04667-x. 
      Epub 2023 Apr 11.