PMID- 37038145 OWN - NLM STAT- MEDLINE DCOM- 20230412 LR - 20230415 IS - 1471-2431 (Electronic) IS - 1471-2431 (Linking) VI - 23 IP - 1 DP - 2023 Apr 11 TI - Health-related quality of life in children under treatment for overweight, obesity or severe obesity: a cross-sectional study in the Netherlands. PG - 167 LID - 10.1186/s12887-023-03973-8 [doi] LID - 167 AB - BACKGROUND: It is unknown whether weight class is associated with impairment of health-related quality of life (HRQOL) for children in the Netherlands. The aim of this study was to explore generic and weight-specific HRQOL in a clinical cohort of children with overweight, obesity or severe obesity aged 5-19 years in the Netherlands. METHODS: 803 children from three clinical cohorts participated: mean age 11.5 (SD 2.9) years, 61.1% girls. The influence of weight class was explored in a subgroup of 425 children (25.2% with overweight, 32.5% obesity and 42.3% severe obesity), of whom the exact International Obesity Task Force (IOTF) BMI class was known. Generic HRQOL was measured by the PedsQL child report. Weight-specific HRQOL was measured by the IWQOL-Kids child or parent report. Average total, subscale and item scores were reported and the influence of the IOTF BMI class analyzed by multiple linear regression, corrected for age and sex. RESULTS: Children with severe obesity had lower generic and weight-specific HRQOL scores than those with obesity or overweight. IOTF BMI class was negatively associated with item scores from all subscales, especially physical, social and emotional functioning. Children with overweight reported similar HRQOL total, subscale and item scores to children with obesity. CONCLUSIONS: In the Netherlands, children treated for overweight, obesity or severe obesity experience problems on the majority of items within all subscales of generic and weight-specific HRQOL. Children with severe obesity especially report significantly more challenges due to their weight than children with obesity or overweight. CI - (c) 2023. The Author(s). FAU - van der Voorn, Bibian AU - van der Voorn B AD - Faculty of Science, Department of Health Sciences, Section Youth and Lifestyle, Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands. b.van.der.voorn@vu.nl. FAU - Camfferman, R AU - Camfferman R AD - Faculty of Science, Department of Health Sciences, Section Youth and Lifestyle, Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands. FAU - Seidell, J C AU - Seidell JC AD - Faculty of Science, Department of Health Sciences, Section Youth and Lifestyle, Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands. FAU - Halberstadt, J AU - Halberstadt J AD - Faculty of Science, Department of Health Sciences, Section Youth and Lifestyle, Vrije Universiteit Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, The Netherlands. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230411 PL - England TA - BMC Pediatr JT - BMC pediatrics JID - 100967804 SB - IM MH - Female MH - Child MH - Humans MH - Male MH - *Overweight/therapy/psychology MH - Quality of Life/psychology MH - *Obesity, Morbid/therapy MH - Cross-Sectional Studies MH - Netherlands MH - Body Mass Index MH - Obesity/psychology PMC - PMC10088296 OTO - NOTNLM OT - Europe OT - Overweight OT - Patient-reported outcome measures OT - Pediatric obesity OT - Quality of life COIS- The authors declare no conflict of interest. EDAT- 2023/04/11 06:00 MHDA- 2023/04/12 06:42 PMCR- 2023/04/11 CRDT- 2023/04/10 23:45 PHST- 2022/08/12 00:00 [received] PHST- 2023/03/26 00:00 [accepted] PHST- 2023/04/12 06:42 [medline] PHST- 2023/04/10 23:45 [entrez] PHST- 2023/04/11 06:00 [pubmed] PHST- 2023/04/11 00:00 [pmc-release] AID - 10.1186/s12887-023-03973-8 [pii] AID - 3973 [pii] AID - 10.1186/s12887-023-03973-8 [doi] PST - epublish SO - BMC Pediatr. 2023 Apr 11;23(1):167. doi: 10.1186/s12887-023-03973-8.