PMID- 3703917 OWN - NLM STAT- MEDLINE DCOM- 19860530 LR - 20190919 IS - 0031-6989 (Print) IS - 0031-6989 (Linking) VI - 18 IP - 2 DP - 1986 Feb TI - Episodic secretion of met-enkephalin immunoreactive material in human plasma and CSF. PG - 155-9 AB - Plasma and CSF met-enkephalin immunoreactive material (ME-IR) concentrations were measured in 5 subjects at different hours of the day. Within the 24 hrs CSF ME-IR concentrations ranged in the same patient from 20 to 5000 pg/ml. Plasma ME-IR concentrations presented a circadian rhythm with lower values between 4:00 and 8:00 p.m. FAU - Govoni, S AU - Govoni S FAU - Salar, G AU - Salar G FAU - Colombo, F AU - Colombo F FAU - Pasinetti, G AU - Pasinetti G FAU - Trabucchi, M AU - Trabucchi M FAU - Mingrino, S AU - Mingrino S LA - eng PT - Journal Article PL - United States TA - Pharmacol Res Commun JT - Pharmacological research communications JID - 0236354 RN - 58569-55-4 (Enkephalin, Methionine) SB - IM MH - Adult MH - Aged MH - Enkephalin, Methionine/blood/cerebrospinal fluid/*metabolism MH - Humans MH - Male MH - Middle Aged MH - Radioimmunoassay MH - Time Factors EDAT- 1986/02/01 00:00 MHDA- 1986/02/01 00:01 CRDT- 1986/02/01 00:00 PHST- 1986/02/01 00:00 [pubmed] PHST- 1986/02/01 00:01 [medline] PHST- 1986/02/01 00:00 [entrez] AID - 10.1016/0031-6989(86)90143-8 [doi] PST - ppublish SO - Pharmacol Res Commun. 1986 Feb;18(2):155-9. doi: 10.1016/0031-6989(86)90143-8.