PMID- 37041742
OWN - NLM
STAT- MEDLINE
DCOM- 20231113
LR  - 20240218
IS  - 1751-7893 (Electronic)
IS  - 1751-7885 (Print)
IS  - 1751-7885 (Linking)
VI  - 17
IP  - 11
DP  - 2023 Nov
TI  - The association between early traumatic experiences and the five domains of 
      negative symptoms in participants at clinical high risk for psychosis.
PG  - 1131-1135
LID - 10.1111/eip.13418 [doi]
AB  - AIM: Youth at clinical high risk (CHR) for psychosis have high rates of early 
      life trauma, but it is unclear how trauma exposure impacts later negative symptom 
      severity in CHR. The current study examined the association between early 
      childhood trauma and the five domains of negative symptoms (anhedonia, avolition, 
      asociality, blunted affect, alogia). METHOD: Eighty nine participants completed 
      interviewer-rated measures of childhood trauma and abuse experienced before age 
      16, psychosis risk, and negative symptoms. RESULTS: Higher global negative 
      symptom severity was associated with greater exposure to childhood psychological 
      bullying, physical bullying, emotional neglect, psychological abuse, and physical 
      abuse. Greater severity of avolition and asociality was associated with physical 
      bullying. Greater severity of avolition was associated with emotional neglect. 
      CONCLUSION: Early adversity and childhood trauma is associated with negative 
      symptoms during adolescence and early adulthood among participants at CHR for 
      psychosis.
CI  - (c) 2023 The Authors. Early Intervention in Psychiatry published by John Wiley & 
      Sons Australia, Ltd.
FAU - Ayawvi, Gifty
AU  - Ayawvi G
AD  - Department of Psychology, University of Georgia, Athens, Georgia, USA.
FAU - Berglund, Alysia M
AU  - Berglund AM
AD  - Department of Psychology, University of Georgia, Athens, Georgia, USA.
FAU - James, Sydney H
AU  - James SH
AD  - Department of Psychology, University of Georgia, Athens, Georgia, USA.
FAU - Luther, Lauren
AU  - Luther L
AD  - Department of Psychology, University of Georgia, Athens, Georgia, USA.
FAU - Walker, Elaine F
AU  - Walker EF
AD  - Department of Psychology, Emory University, Atlanta, Georgia, USA.
FAU - Mittal, Vijay A
AU  - Mittal VA
AD  - Department of Psychology, Northwestern University, Evanston, Illinois, USA.
FAU - Strauss, Gregory P
AU  - Strauss GP
AUID- ORCID: 0000-0002-7218-5169
AD  - Department of Psychology, University of Georgia, Athens, Georgia, USA.
LA  - eng
GR  - R01 MH116039/MH/NIMH NIH HHS/United States
GR  - R21 MH119438/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20230411
PL  - Australia
TA  - Early Interv Psychiatry
JT  - Early intervention in psychiatry
JID - 101320027
SB  - IM
MH  - Child, Preschool
MH  - Adolescent
MH  - Humans
MH  - Child
MH  - Adult
MH  - *Adult Survivors of Child Abuse/psychology
MH  - *Psychotic Disorders/psychology
MH  - *Child Abuse/psychology
MH  - Mood Disorders
MH  - Anhedonia
PMC - PMC10564962
MID - NIHMS1888124
OTO - NOTNLM
OT  - abuse
OT  - bullying
OT  - negative symptoms
OT  - neglect
OT  - ultra high-risk
COIS- Conflict of Interest Disclosure: Gregory P. Strauss is one of the original 
      developers of the brief negative symptom scale (BNSS) and receives royalties and 
      consultation fees from Medavante-ProPhase LLC in connection with commercial use 
      of the BNSS and other professional activities; these fees are donated to the 
      Brain and Behaviour Research Foundation. Gregory P. Strauss has received 
      honoraria and travel support from ProPhaseLLC for training pharmaceutical company 
      raters on the BNSS. Gregory P. Strauss has consulted for minerva neurosciences, 
      acadia and lundbeck. All other authors have no relevant disclosures.
EDAT- 2023/04/13 06:00
MHDA- 2023/11/13 06:42
PMCR- 2024/11/01
CRDT- 2023/04/12 01:32
PHST- 2023/02/02 00:00 [revised]
PHST- 2022/09/02 00:00 [received]
PHST- 2023/03/28 00:00 [accepted]
PHST- 2024/11/01 00:00 [pmc-release]
PHST- 2023/11/13 06:42 [medline]
PHST- 2023/04/13 06:00 [pubmed]
PHST- 2023/04/12 01:32 [entrez]
AID - 10.1111/eip.13418 [doi]
PST - ppublish
SO  - Early Interv Psychiatry. 2023 Nov;17(11):1131-1135. doi: 10.1111/eip.13418. Epub 
      2023 Apr 11.