PMID- 37048804
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230415
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 12
IP  - 7
DP  - 2023 Apr 5
TI  - Minimal Clinically Important Differences in Inspiratory Muscle Function Variables 
      after a Respiratory Muscle Training Programme in Individuals with Long-Term 
      Post-COVID-19 Symptoms.
LID - 10.3390/jcm12072720 [doi]
LID - 2720
AB  - OBJECTIVE: To establish the minimal clinically important difference (MCID) for 
      inspiratory muscle strength (MIP) and endurance (IME) in individuals with 
      long-term post-COVID-19 symptoms, as well as to ascertain which of the variables 
      has a greater discriminatory capacity and to compare changes between individuals 
      classified by the MCID. DESIGN: Secondary analysis of randomised controlled trial 
      of data from 42 individuals who performed an 8-week intervention of respiratory 
      muscle training programme. RESULTS: A change of at least 18 cmH(2)O and 22.1% of 
      that predicted for MIP and 328.5s for IME represented the MCID. All variables 
      showed acceptable discrimination between individuals who classified as "improved" 
      and those classified as "stable/not improved" (area under the curve >/=0.73). MIP 
      was the variable with the best discriminative ability when expressed as a 
      percentage of prediction (Youden index, 0.67; sensitivity, 76.9%; specificity, 
      89.7%). Participants classified as "improved" had significantly greater 
      improvements in quality of life and lung function compared with the participants 
      classified as "stable/not improved". CONCLUSION: In individuals with long-term 
      post-COVID-19 symptoms, the inspiratory muscle function variables had an 
      acceptable discriminative ability to assess the efficacy of a respiratory muscle 
      training programme. MIP was the variable with the best discriminative ability, 
      showing better overall performance when expressed as a percentage of prediction.
FAU - Del Corral, Tamara
AU  - Del Corral T
AUID- ORCID: 0000-0002-3144-5411
AD  - Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, 
      Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 
      Madrid, Spain.
AD  - Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), 
      28040 Madrid, Spain.
FAU - Fabero-Garrido, Raul
AU  - Fabero-Garrido R
AUID- ORCID: 0000-0002-6565-4967
AD  - Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, 
      Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 
      Madrid, Spain.
FAU - Plaza-Manzano, Gustavo
AU  - Plaza-Manzano G
AUID- ORCID: 0000-0003-1596-5027
AD  - Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, 
      Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 
      Madrid, Spain.
AD  - Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), 
      28040 Madrid, Spain.
FAU - Fernandez-de-Las-Penas, Cesar
AU  - Fernandez-de-Las-Penas C
AUID- ORCID: 0000-0003-3772-9690
AD  - Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical 
      Medicine, Universidad Rey Juan Carlos, 28922 Alcorcon, Spain.
AD  - Catedra Institucional en Docencia, Clinica e Investigacion en Fisioterapia, 
      Terapia Manual, Puncion Seca y Ejercicio Terapeutico, Universidad Rey Juan 
      Carlos, 28922 Alcorcon, Spain.
FAU - Navarro-Santana, Marcos Jose
AU  - Navarro-Santana MJ
AUID- ORCID: 0000-0002-6065-9283
AD  - Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, 
      Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 
      Madrid, Spain.
FAU - Lopez-de-Uralde-Villanueva, Ibai
AU  - Lopez-de-Uralde-Villanueva I
AUID- ORCID: 0000-0001-7474-5257
AD  - Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, 
      Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 
      Madrid, Spain.
AD  - Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), 
      28040 Madrid, Spain.
LA  - eng
PT  - Journal Article
DEP - 20230405
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC10095020
OTO - NOTNLM
OT  - SARS-CoV-2
OT  - inspiratory muscle training
OT  - minimal clinically important difference
OT  - responsiveness
COIS- The authors declare no conflict of interest.
EDAT- 2023/04/14 06:00
MHDA- 2023/04/14 06:01
PMCR- 2023/04/05
CRDT- 2023/04/13 01:20
PHST- 2023/03/14 00:00 [received]
PHST- 2023/03/31 00:00 [revised]
PHST- 2023/04/03 00:00 [accepted]
PHST- 2023/04/14 06:01 [medline]
PHST- 2023/04/13 01:20 [entrez]
PHST- 2023/04/14 06:00 [pubmed]
PHST- 2023/04/05 00:00 [pmc-release]
AID - jcm12072720 [pii]
AID - jcm-12-02720 [pii]
AID - 10.3390/jcm12072720 [doi]
PST - epublish
SO  - J Clin Med. 2023 Apr 5;12(7):2720. doi: 10.3390/jcm12072720.