PMID- 37049408
OWN - NLM
STAT- MEDLINE
DCOM- 20230414
LR  - 20230415
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 15
IP  - 7
DP  - 2023 Mar 24
TI  - Associations between Vitality/Nutrition and the Other Domains of Intrinsic 
      Capacity Based on Data from the INSPIRE ICOPE-Care Program.
LID - 10.3390/nu15071567 [doi]
LID - 1567
AB  - BACKGROUND: The vitality domain of intrinsic capacity (IC) represents the 
      synthesis of biological interactions and metabolism. As part of the Integrated 
      Care for Older People (ICOPE) program developed by the World Health Organization 
      (WHO), vitality focuses on the nutritional status of older adults. The objective 
      of this work was to describe the vitality domain of IC in community-dwelling 
      older people and to examine the associations of the vitality components (appetite 
      loss and weight loss) with the other IC domains assessed within the framework of 
      ICOPE. METHODS: Cross-sectional data were obtained between January 2020 and 
      February 2022 through the INSPIRE-ICOPE-Care program, a real-life ICOPE 
      implementation initiative developed in the Occitania region of France. 
      Participants were men and women aged 60 and older, looking for primary care 
      services within the French healthcare system. RESULTS: Appetite loss was reported 
      by 14.0% (2013) of the participants, and weight loss by 12.4% (1788). A total of 
      863 participants (6.01%) declaring weight loss also suffered from appetite loss. 
      In total, 2910 participants (20.27%) screened positive for the domain of 
      vitality. Appetite loss was significantly associated with positive screenings for 
      the domains of cognition (OR = 2.14 [1.84;2.48]), vision (OR = 1.51 [1.28;1.79]), 
      hearing (OR = 1.18 [1.01;1.37]), psychology (OR = 3.95 [3.46;4.52]), and 
      locomotion 'OR = 2.19 [1.91;2.51]). We found significant associations of weight 
      loss with the IC domains of cognition (OR = 1.65 [1.42;1.93]), psychology (OR = 
      1.80 [1.56;2.07]), locomotion (OR = 1.64 [1.41;1.91]), vision (OR = 1.24 
      [1.04;1.47]), and hearing (OR = 1.32 [1.12;1.55]). People reporting simultaneous 
      appetite and weight loss showed higher odds of screening positive for 
      psychological (OR = 5.33 [4.53;6.27]) and locomotion impairments (OR = 3.38 
      [2.88;3.98]). CONCLUSIONS: Appetite and weight loss are common among older people 
      and are related to other potential IC impairments, especially psychological and 
      locomotion. Further studies are needed to explore the longitudinal associations 
      of vitality with the incidence of clinically meaningful declines in the other IC 
      domains.
FAU - Gaussens, Luc
AU  - Gaussens L
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
FAU - Gonzalez-Bautista, Emmanuel
AU  - Gonzalez-Bautista E
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
FAU - Bonnefoy, Marc
AU  - Bonnefoy M
AD  - Service de Medecine Geriatrique, CHU Lyon, Groupement Hospitalier Sud, 69495 
      Pierre-Benite, France.
FAU - Briand, Marguerite
AU  - Briand M
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
FAU - Tavassoli, Neda
AU  - Tavassoli N
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
FAU - De Souto Barreto, Philipe
AU  - De Souto Barreto P
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
AD  - CERPOP UMR 1295, University of Toulouse III, Inserm, UPS, 31062 Toulouse, France.
FAU - Rolland, Yves
AU  - Rolland Y
AD  - Gerontopole de Toulouse, Institut du Vieillissement, Centre 
      Hospitalo-Universitaire de Toulouse, 31300 Toulouse, France.
AD  - CERPOP UMR 1295, University of Toulouse III, Inserm, UPS, 31062 Toulouse, France.
FAU - On Behalf Of The Gegn Group
AU  - On Behalf Of The Gegn Group
LA  - eng
PT  - Journal Article
DEP - 20230324
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
SB  - IM
MH  - Male
MH  - Humans
MH  - Female
MH  - Middle Aged
MH  - Aged
MH  - *Nutritional Status
MH  - Cross-Sectional Studies
MH  - *Weight Loss
MH  - Appetite
MH  - Cognition
PMC - PMC10096560
OTO - NOTNLM
OT  - ICOPE
OT  - appetite
OT  - intrinsic capacity
OT  - older people
OT  - prevention
OT  - vitality
OT  - weight loss
COIS- The authors declare no conflict of interest.
EDAT- 2023/04/14 06:00
MHDA- 2023/04/14 06:41
PMCR- 2023/03/24
CRDT- 2023/04/13 01:24
PHST- 2023/02/26 00:00 [received]
PHST- 2023/03/19 00:00 [revised]
PHST- 2023/03/21 00:00 [accepted]
PHST- 2023/04/14 06:41 [medline]
PHST- 2023/04/13 01:24 [entrez]
PHST- 2023/04/14 06:00 [pubmed]
PHST- 2023/03/24 00:00 [pmc-release]
AID - nu15071567 [pii]
AID - nutrients-15-01567 [pii]
AID - 10.3390/nu15071567 [doi]
PST - epublish
SO  - Nutrients. 2023 Mar 24;15(7):1567. doi: 10.3390/nu15071567.