PMID- 37070890
OWN - NLM
STAT- MEDLINE
DCOM- 20230420
LR  - 20230504
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 27
IP  - 7
DP  - 2023 Apr
TI  - The association between chronic venous disease and knee osteoarthritis.
PG  - 2899-2907
LID - 31921 [pii]
LID - 10.26355/eurrev_202304_31921 [doi]
AB  - OBJECTIVE: Chronic venous disease (CVD) and knee osteoarthritis (KOA) are two 
      common diseases in the elderly. Both share common risk factors, such as age, sex, 
      and obesity, and are believed to be associated with inflammatory conditions and 
      venous stasis. However, studies of the association between CVD and KOA are 
      limited, especially in the elderly. To investigate the association between CVD 
      and KOA and their effects on pain and functional status in the elderly at the 
      Rheumatology Clinic of University Medical Center Ho Chi Minh City (HCMC). 
      PATIENTS AND METHODS: This cross-sectional study included 222 elderly patients 
      (aged >/=60 years) at the Rheumatology Clinic of University Medical Center HCMC 
      from December 2019 to June 2020, including 167 with and 55 without KOA. Patient 
      data were collected for both groups, including demographics, symptoms, clinical 
      signs, and diagnostic tests for KOA and CVD, including knee radiographs and 
      duplex scanning of the lower extremity veins. RESULTS: CVD was a common 
      comorbidity among elderly patients with KOA (73.65% vs. 58.18%; p = 0.030). CVD 
      symptoms did not differ significantly between patients with and without KOA. 
      After adjusting for age, sex, body mass index, and some comorbid conditions, the 
      differences in CVD incidence between the groups remained significant (odds ratio 
      = 2.46, 95% confidence interval: 1.20-5.06; p = 0.014). Visual Analog Scale and 
      Western Ontario and McMaster Universities Osteoarthritis Index pain scores were 
      higher in elderly patients with KOA and CVD. CONCLUSIONS: CVD is common in 
      elderly patients with KOA. While age, sex, and weight are risk factors for both 
      conditions, there is an independent association between them. Patients comorbid 
      with KOA and CVD have more pain and limited functional status.
FAU - Cao, T-N
AU  - Cao TN
AD  - Department of Geriatrics and Gerontology, University of Medicine and Pharmacy at 
      Ho Chi Minh City, Ho Chi Minh City, Vietnam. bsnguyenminhduc@pnt.edu.vn.
FAU - Nguyen, C-T
AU  - Nguyen CT
FAU - Nguyen, M-D
AU  - Nguyen MD
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
SB  - IM
MH  - Aged
MH  - Humans
MH  - *Osteoarthritis, Knee/epidemiology/complications
MH  - Cross-Sectional Studies
MH  - Pain/etiology
MH  - Risk Factors
MH  - Chronic Disease
MH  - *Cardiovascular Diseases/complications
EDAT- 2023/04/19 06:00
MHDA- 2023/04/20 06:41
CRDT- 2023/04/18 09:23
PHST- 2023/04/20 06:41 [medline]
PHST- 2023/04/18 09:23 [entrez]
PHST- 2023/04/19 06:00 [pubmed]
AID - 31921 [pii]
AID - 10.26355/eurrev_202304_31921 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2023 Apr;27(7):2899-2907. doi: 
      10.26355/eurrev_202304_31921.