PMID- 37070962
OWN - NLM
STAT- MEDLINE
DCOM- 20230518
LR  - 20230614
IS  - 1748-1716 (Electronic)
IS  - 1748-1708 (Linking)
VI  - 238
IP  - 2
DP  - 2023 Jun
TI  - Complexity analysis from EEG data in congestive heart failure: A study via 
      approximate entropy.
PG  - e13979
LID - 10.1111/apha.13979 [doi]
AB  - AIM: Congestive heart failure (CHF) is a very complex clinical syndrome that may 
      lead to ischemic cerebral hypoxia condition. The aim of the present study is to 
      analyze the effects of CHF on brain activity through electroencephalographic 
      (EEG) complexity measures, like approximate entropy (ApEn). METHODS: Twenty 
      patients with CHF and 18 healthy elderly people were recruited. ApEn values were 
      evaluated in the total spectrum (0.2-47 Hz) and main EEG frequency bands: delta 
      (2-4 Hz), theta (4-8 Hz), alpha 1 (8-11 Hz), alpha 2 (11-13 Hz), beta 1 
      (13-20 Hz), beta 2 (20-30 Hz), and gamma (30-45 Hz) to identify differences 
      between CHF group and control. Moreover, a correlation analysis was performed 
      between ApEn parameters and clinical data (i.e., B-type natriuretic peptides 
      (BNP), New York Heart Association (NYHA), and systolic blood pressure (SBP)) 
      within the CHF group. RESULTS: Statistical topographic maps showed statistically 
      significant differences between the two groups in the total spectrum and theta 
      frequency band. Within the CHF group, significant negative correlations were 
      found between total ApEn and BNP in O2 channel and between theta ApEn and NYHA 
      scores in Fp1, Fp2, and Fz channels; instead, a significant positive correlation 
      was found between theta ApEn and SBP in C3 channel and a nearly significant 
      positive correlation was obtained between theta ApEn and SBP in F4 channel. 
      CONCLUSION: EEG abnormalities in CHF are very similar to those observed in 
      cognitive-impaired patients, suggesting analogies between the effects of 
      neurodegeneration and brain chronic hypovolaemia due to heart disorder and 
      underlying high brain sensitivity to CHF.
CI  - (c) 2023 The Authors. Acta Physiologica published by John Wiley & Sons Ltd on 
      behalf of Scandinavian Physiological Society.
FAU - Cacciotti, Alessia
AU  - Cacciotti A
AD  - Brain Connectivity Laboratory, Department of Neuroscience and 
      Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
AD  - Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 
      Como, Italy.
FAU - Pappalettera, Chiara
AU  - Pappalettera C
AD  - Brain Connectivity Laboratory, Department of Neuroscience and 
      Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
AD  - Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 
      Como, Italy.
FAU - Miraglia, Francesca
AU  - Miraglia F
AD  - Brain Connectivity Laboratory, Department of Neuroscience and 
      Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
AD  - Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 
      Como, Italy.
FAU - Valeriani, Lavinia
AU  - Valeriani L
AD  - Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 
      Como, Italy.
AD  - Fondazione Antea, Rome, Italy.
FAU - Judica, Elda
AU  - Judica E
AD  - Department of Neurorehabilitation Sciences, Casa Cura Policlinico, Milan, Italy.
FAU - Rossini, Paolo Maria
AU  - Rossini PM
AD  - Brain Connectivity Laboratory, Department of Neuroscience and 
      Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
FAU - Vecchio, Fabrizio
AU  - Vecchio F
AUID- ORCID: 0000-0002-6004-9522
AD  - Brain Connectivity Laboratory, Department of Neuroscience and 
      Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
AD  - Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 
      Como, Italy.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230430
PL  - England
TA  - Acta Physiol (Oxf)
JT  - Acta physiologica (Oxford, England)
JID - 101262545
SB  - IM
MH  - Humans
MH  - Aged
MH  - Entropy
MH  - *Electroencephalography
MH  - *Heart Failure
MH  - Brain
MH  - Systems Analysis
OTO - NOTNLM
OT  - EEG
OT  - congestive heart failure
OT  - entropy
EDAT- 2023/04/19 06:00
MHDA- 2023/05/18 06:42
CRDT- 2023/04/18 09:52
PHST- 2023/04/12 00:00 [revised]
PHST- 2023/01/13 00:00 [received]
PHST- 2023/04/14 00:00 [accepted]
PHST- 2023/05/18 06:42 [medline]
PHST- 2023/04/19 06:00 [pubmed]
PHST- 2023/04/18 09:52 [entrez]
AID - 10.1111/apha.13979 [doi]
PST - ppublish
SO  - Acta Physiol (Oxf). 2023 Jun;238(2):e13979. doi: 10.1111/apha.13979. Epub 2023 
      Apr 30.