PMID- 3707656 OWN - NLM STAT- MEDLINE DCOM- 19860528 LR - 20131121 IS - 0004-4172 (Print) IS - 0004-4172 (Linking) VI - 36 IP - 2A DP - 1986 Feb TI - Monitored long-term treatment with ibopamine in patients suffering from severe congestive heart failure. PG - 394-7 AB - 50 patients with congestive heart failure underwent monitored long-term treatment aimed at evaluating the effect of ibopamine (SB-7505), the 3,4-diisobutyryl ester of N-methyldopamine, on their condition. Ibopamine was administered alone or in combination with traditional therapy mainly at a dose of 100 mg t.i.d. Clinical scores and NYHA (New York Heart Association) functional classes improved. Biochemical parameters showed no adverse modifications. Mild transient side-effects probably related to ibopamine occurred in two patients. FAU - Avanzini, Z AU - Avanzini Z FAU - Bellogini, G C AU - Bellogini GC FAU - Brusoni, B AU - Brusoni B FAU - Ciampani, N AU - Ciampani N FAU - Dei Cas, L AU - Dei Cas L FAU - Gazzola, U AU - Gazzola U FAU - Maggi, G C AU - Maggi GC FAU - Mangiavacchi, M AU - Mangiavacchi M FAU - Metra, M AU - Metra M FAU - Pinca, L AU - Pinca L AU - et al. LA - eng PT - Journal Article PL - Germany TA - Arzneimittelforschung JT - Arzneimittel-Forschung JID - 0372660 RN - 0 (Cardiotonic Agents) RN - 8ZCA2I2L11 (ibopamine) RN - R7339QLN1C (Deoxyepinephrine) RN - VTD58H1Z2X (Dopamine) SB - IM MH - Adult MH - Aged MH - Body Weight/drug effects MH - Cardiotonic Agents/adverse effects/*therapeutic use MH - Chronic Disease MH - Deoxyepinephrine/adverse effects/*analogs & derivatives/therapeutic use MH - Dopamine/*analogs & derivatives MH - Female MH - Heart Failure/*drug therapy/physiopathology MH - Heart Rate/drug effects MH - Hemodynamics/drug effects MH - Humans MH - Male MH - Middle Aged MH - Monitoring, Physiologic MH - Time Factors EDAT- 1986/02/01 00:00 MHDA- 1986/02/01 00:01 CRDT- 1986/02/01 00:00 PHST- 1986/02/01 00:00 [pubmed] PHST- 1986/02/01 00:01 [medline] PHST- 1986/02/01 00:00 [entrez] PST - ppublish SO - Arzneimittelforschung. 1986 Feb;36(2A):394-7.