PMID- 37080454
OWN - NLM
STAT- MEDLINE
DCOM- 20230628
LR  - 20230628
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 175
DP  - 2023 Jul
TI  - Perioperative Predictors in Patients Undergoing Lateral Lumbar Interbody Fusion 
      for Minimum Clinically Important Difference Achievement.
PG  - e914-e924
LID - S1878-8750(23)00527-2 [pii]
LID - 10.1016/j.wneu.2023.04.042 [doi]
AB  - OBJECTIVE: To identify perioperative predictors of minimum clinically important 
      difference (MCID) for patients undergoing lateral lumbar interbody fusion (LLIF) 
      for the patient-reported outcome measures (PROMs) of Patient-Reported Outcomes 
      Measurement Information System Physical Function (PROMIS-PF), visual analog scale 
      (VAS) back, VAS leg, Oswestry Disability Index (ODI), and Patient Health 
      Questionnaire-9 (PHQ-9). METHODS: Patients undergoing LLIF were identified 
      through retrospective review of a single-surgeon database. Overall MCID 
      achievement was determined as the number of unique patients achieving DeltaPROM 
      thresholds of PROMIS-PF = 4.5, VAS back = 2.1, VAS leg = 2.8, ODI = 14.9, and 
      PHQ-9 = 3.0 over a 2-year postoperative period. Univariate and multivariable 
      logistic regression were used to determine perioperative predictors for MCID 
      achievement. RESULTS: Two-hundred and ninety patients were identified. For 
      PROMIS-PF MCID achievement, increased preoperative PROMIS-PF and postoperative 
      day (POD) 1 VAS pain were significant negative predictors. For VAS back, primary 
      fusion with revision decompression was a negative predictor, whereas increased 
      preoperative VAS back score was a positive predictor of MCID achievement. For VAS 
      leg, increased preoperative VAS leg score was a positive predictor. For ODI, 
      increased POD 0 VAS pain score was a negative predictor, whereas increased 
      preoperative ODI was a positive predictor. For PHQ-9, increased preoperative 
      PHQ-9 score was a positive predictor. CONCLUSIONS: In patients undergoing LLIF, 
      perioperative predictors for MCID achievement were highly dependent on PROM. 
      Preoperative PROM was the most consistent perioperative predictor for achieving 
      MCID. Increased acute postoperative pain and primary fusion after failed index 
      decompression were significant predictors of failing to achieve MCID. Surgeons 
      may use these findings in prognostication and management of postoperative 
      expectations.
CI  - Copyright (c) 2023 Elsevier Inc. All rights reserved.
FAU - Nie, James W
AU  - Nie JW
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Hartman, Timothy J
AU  - Hartman TJ
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Oyetayo, Omolabake O
AU  - Oyetayo OO
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - MacGregor, Keith R
AU  - MacGregor KR
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Zheng, Eileen
AU  - Zheng E
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Federico, Vincent P
AU  - Federico VP
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Massel, Dustin H
AU  - Massel DH
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Sayari, Arash J
AU  - Sayari AJ
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, 
      Illinois, USA. Electronic address: kern.singh@rushortho.com.
LA  - eng
PT  - Journal Article
DEP - 20230418
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Humans
MH  - Treatment Outcome
MH  - *Lumbar Vertebrae/surgery
MH  - Retrospective Studies
MH  - Pain, Postoperative
MH  - *Spinal Fusion
OTO - NOTNLM
OT  - Lateral lumbar interbody fusion
OT  - Minimum clinically important difference
OT  - Patient-reported outcome measures
EDAT- 2023/04/21 00:42
MHDA- 2023/06/28 06:42
CRDT- 2023/04/20 19:27
PHST- 2022/11/29 00:00 [received]
PHST- 2023/04/10 00:00 [revised]
PHST- 2023/04/11 00:00 [accepted]
PHST- 2023/06/28 06:42 [medline]
PHST- 2023/04/21 00:42 [pubmed]
PHST- 2023/04/20 19:27 [entrez]
AID - S1878-8750(23)00527-2 [pii]
AID - 10.1016/j.wneu.2023.04.042 [doi]
PST - ppublish
SO  - World Neurosurg. 2023 Jul;175:e914-e924. doi: 10.1016/j.wneu.2023.04.042. Epub 
      2023 Apr 18.