PMID- 37081512 OWN - NLM STAT- MEDLINE DCOM- 20230424 LR - 20230424 IS - 1746-1596 (Electronic) IS - 1746-1596 (Linking) VI - 18 IP - 1 DP - 2023 Apr 20 TI - Role and research progress of hematological markers in laryngeal squamous cell carcinoma. PG - 50 LID - 10.1186/s13000-023-01335-7 [doi] LID - 50 AB - Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC. CI - (c) 2023. The Author(s). FAU - Qi, Hui AU - Qi H AUID- ORCID: 0000-0003-3890-1405 AD - Nursing College, Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China. qihuisx@163.com. AD - Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China. qihuisx@163.com. LA - eng PT - Journal Article PT - Review DEP - 20230420 PL - England TA - Diagn Pathol JT - Diagnostic pathology JID - 101251558 SB - IM MH - Humans MH - Squamous Cell Carcinoma of Head and Neck MH - *Laryngeal Neoplasms/diagnosis/pathology MH - *Head and Neck Neoplasms MH - *Carcinoma, Squamous Cell/diagnosis/pathology MH - Prognosis PMC - PMC10120220 OTO - NOTNLM OT - Hematological markers OT - Inflammation OT - Laryngeal squamous cell carcinoma OT - Prognosis OT - Tumor microenvironment COIS- The author declare that they have no competing interests. EDAT- 2023/04/21 00:42 MHDA- 2023/04/24 06:42 PMCR- 2023/04/20 CRDT- 2023/04/20 23:41 PHST- 2022/10/14 00:00 [received] PHST- 2023/04/03 00:00 [accepted] PHST- 2023/04/24 06:42 [medline] PHST- 2023/04/21 00:42 [pubmed] PHST- 2023/04/20 23:41 [entrez] PHST- 2023/04/20 00:00 [pmc-release] AID - 10.1186/s13000-023-01335-7 [pii] AID - 1335 [pii] AID - 10.1186/s13000-023-01335-7 [doi] PST - epublish SO - Diagn Pathol. 2023 Apr 20;18(1):50. doi: 10.1186/s13000-023-01335-7.