PMID- 37091268
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230425
IS  - 2296-875X (Print)
IS  - 2296-875X (Electronic)
IS  - 2296-875X (Linking)
VI  - 10
DP  - 2023
TI  - A nomogram for predicting postoperative overall survival of patients with lung 
      squamous cell carcinoma: A SEER-based study.
PG  - 1143035
LID - 10.3389/fsurg.2023.1143035 [doi]
LID - 1143035
AB  - BACKGROUND: Lung squamous cell carcinoma (LSCC) is a common subtype of non-small 
      cell lung cancer. Our study aimed to construct and validate a nomogram for 
      predicting overall survival (OS) for postoperative LSCC patients. METHODS: A 
      total of 8,078 patients eligible for recruitment between 2010 and 2015 were 
      selected from the Surveillance, Epidemiology, and End Results database. Study 
      outcomes were 1-, 2- and 3-year OS. Analyses performed included univariate and 
      multivariate Cox regression, receiver operating characteristic (ROC) curve 
      construction, calibration plotting, decision curve analysis (DCA) and 
      Kaplan-Meier survival plotting. RESULTS: Seven variables were selected to 
      establish our predictive nomogram. Areas under the ROC curves were 0.658, 0.651 
      and 0.647 for the training cohort and 0.673, 0.667 and 0.658 for the validation 
      cohort at 1-, 2- and 3-year time-points, respectively. Calibration curves 
      confirmed satisfactory consistencies between nomogram-predicted and observed 
      survival probabilities, while DCA confirmed significant clinical usefulness of 
      our model. For risk stratification, patients were divided into three risk groups 
      with significant differences in OS on Kaplan-Meier analysis (P < 0.001). 
      CONCLUSION: Here, we designed and validated a prognostic nomogram for OS in 
      postoperative LSCC patients. Application of our model in the clinical setting may 
      assist clinicians in evaluating patient prognosis and providing highly 
      individualized therapy.
CI  - (c) 2023 Rao, Yu, Zhang, Wang, Wang and Wang.
FAU - Rao, Jin
AU  - Rao J
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
FAU - Yu, Yue
AU  - Yu Y
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
FAU - Zhang, Li
AU  - Zhang L
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
AD  - Medical College, Guangxi University, Nanning, China.
FAU - Wang, Xuefu
AU  - Wang X
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
AD  - School of Health Science and Engineering, University of Shanghai for Science and 
      Technology, Shanghai, China.
FAU - Wang, Pei
AU  - Wang P
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
FAU - Wang, Zhinong
AU  - Wang Z
AD  - Department of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical 
      University, Shanghai, China.
LA  - eng
PT  - Journal Article
DEP - 20230406
PL  - Switzerland
TA  - Front Surg
JT  - Frontiers in surgery
JID - 101645127
PMC - PMC10118027
OTO - NOTNLM
OT  - end results (SEER)
OT  - epidemiology
OT  - lung squamous cell carcinoma (LSCC)
OT  - nomogram
OT  - prognosis
OT  - surgery
OT  - surveillance
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/04/24 06:42
MHDA- 2023/04/24 06:43
PMCR- 2023/04/06
CRDT- 2023/04/24 03:54
PHST- 2023/01/12 00:00 [received]
PHST- 2023/03/20 00:00 [accepted]
PHST- 2023/04/24 06:43 [medline]
PHST- 2023/04/24 06:42 [pubmed]
PHST- 2023/04/24 03:54 [entrez]
PHST- 2023/04/06 00:00 [pmc-release]
AID - 10.3389/fsurg.2023.1143035 [doi]
PST - epublish
SO  - Front Surg. 2023 Apr 6;10:1143035. doi: 10.3389/fsurg.2023.1143035. eCollection 
      2023.