PMID- 37097822
OWN - NLM
STAT- MEDLINE
DCOM- 20230607
LR  - 20230925
IS  - 1531-7056 (Electronic)
IS  - 0267-1379 (Linking)
VI  - 39
IP  - 4
DP  - 2023 Jul 1
TI  - How to recognize and treat rumination syndrome.
PG  - 340-346
LID - 10.1097/MOG.0000000000000937 [doi]
AB  - PURPOSE OF REVIEW: Rumination syndrome (RS) is a functional gastroduodenal 
      disorder characterized by repeated effortless regurgitation or vomiting of 
      recently ingested food without retching. RS generally has been considered a rare 
      entity. However, it has been increasingly recognized that many RS patients are 
      likely to be underdiagnosed. This review discusses how to recognize and manage RS 
      patients in clinical practice. RECENT FINDINGS: A recent epidemiological study 
      that included over 50,000 individuals found that the prevalence of RS around the 
      world is 3.1%. In patients with proton pump inhibitor (PPI)-refractory reflux 
      symptoms, postprandial high-resolution manometry combined with impedance (HRM/Z) 
      reveals that RS accounts for up to 20% of those cases. HRM/Z can be a gold 
      standard for objective RS diagnosis. In addition, off-PPI 24-h impedance pH 
      monitoring can suggest the possibility of RS when it reveals frequent 
      postprandial, non-acid reflux with a high symptom index. Modulated cognitive 
      behavioral therapy (CBT) targeting secondary psychological maintaining mechanisms 
      almost eliminates regurgitation. SUMMARY: The prevalence of RS is higher than 
      generally thought. For patients suspected of RS, HRM/Z is useful to distinguish 
      RS from gastroesophageal reflux disease. CBT can be a highly effective 
      therapeutic option.
CI  - Copyright (c) 2023 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Sawada, Akinari
AU  - Sawada A
AD  - Department of Gastroenterology, Osaka Metropolitan University Graduate School of 
      Medicine, Osaka, Japan.
FAU - Sifrim, Daniel
AU  - Sifrim D
AD  - Wingate Institute of Neurogastroenterology, Blizard Institute, Barts and The 
      London School of Medicine and Dentistry, Queen Mary University of London, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230425
PL  - United States
TA  - Curr Opin Gastroenterol
JT  - Current opinion in gastroenterology
JID - 8506887
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Humans
MH  - *Rumination Syndrome/diagnosis/therapy
MH  - *Gastroesophageal Reflux/diagnosis/therapy/complications
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Manometry
MH  - Electric Impedance
MH  - Esophageal pH Monitoring
EDAT- 2023/04/25 18:42
MHDA- 2023/06/07 06:42
CRDT- 2023/04/25 12:42
PHST- 2023/06/07 06:42 [medline]
PHST- 2023/04/25 18:42 [pubmed]
PHST- 2023/04/25 12:42 [entrez]
AID - 00001574-202307000-00014 [pii]
AID - 10.1097/MOG.0000000000000937 [doi]
PST - ppublish
SO  - Curr Opin Gastroenterol. 2023 Jul 1;39(4):340-346. doi: 
      10.1097/MOG.0000000000000937. Epub 2023 Apr 25.