PMID- 37098403 OWN - NLM STAT- MEDLINE DCOM- 20231023 LR - 20231106 IS - 1534-4436 (Electronic) IS - 1081-1206 (Linking) VI - 131 IP - 4 DP - 2023 Oct TI - A review of food allergy panels and their consequences. PG - 421-426 LID - S1081-1206(23)00268-5 [pii] LID - 10.1016/j.anai.2023.04.011 [doi] AB - Serum immunoglobulin E (IgE) assays to food specific IgE (s-IgE) are useful tools for the confirmation of clinical suspicion of food allergy. However, the specificity of these assays is poor given that sensitization is much more common than clinical food allergy. Therefore, the use of broad panels to assess sensitization to multiple foods often leads to overdiagnosis and unnecessary food avoidance. Unintended consequences that may occur as a result include physical harm, psychological harm, financial cost, opportunity cost, and even worsening of existing health care disparities. Although current guidelines recommend against the use of s-IgE food panel testing, these tests are widely available and frequently used. To limit the negative impacts of s-IgE food panel testing, further work is needed to effectively spread the message that these food panels may cause unintended harm to patients and families. CI - Copyright (c) 2023 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. FAU - Parrish, Christopher P AU - Parrish CP AD - Division of Allergy and Immunology, Departments of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: christopher.parrish@utsouthwestern.edu. LA - eng PT - Journal Article PT - Review DEP - 20230423 PL - United States TA - Ann Allergy Asthma Immunol JT - Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology JID - 9503580 RN - 0 (Allergens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Humans MH - Skin Tests MH - *Food Hypersensitivity/diagnosis/epidemiology MH - Allergens MH - Food MH - Immunoglobulin E EDAT- 2023/04/26 00:41 MHDA- 2023/10/23 12:45 CRDT- 2023/04/25 19:14 PHST- 2023/01/24 00:00 [received] PHST- 2023/03/28 00:00 [revised] PHST- 2023/04/10 00:00 [accepted] PHST- 2023/10/23 12:45 [medline] PHST- 2023/04/26 00:41 [pubmed] PHST- 2023/04/25 19:14 [entrez] AID - S1081-1206(23)00268-5 [pii] AID - 10.1016/j.anai.2023.04.011 [doi] PST - ppublish SO - Ann Allergy Asthma Immunol. 2023 Oct;131(4):421-426. doi: 10.1016/j.anai.2023.04.011. Epub 2023 Apr 23.