PMID- 37100366
OWN - NLM
STAT- MEDLINE
DCOM- 20230619
LR  - 20231116
IS  - 1096-0953 (Electronic)
IS  - 0013-9351 (Linking)
VI  - 231
IP  - Pt 1
DP  - 2023 Aug 15
TI  - Environmental sustainable: Biogenic copper oxide nanoparticles as nano-pesticides 
      for investigating bioactivities against phytopathogens.
PG  - 115941
LID - S0013-9351(23)00733-8 [pii]
LID - 10.1016/j.envres.2023.115941 [doi]
AB  - Endocrine-disrupting chemicals (EDCs) are of interest in human physiopathology 
      and have been extensively studied for their effects on the endocrine system. 
      Research also focuses on the environmental impact of EDCs, including pesticides 
      and engineered nanoparticles, and their toxicity to organisms. Green 
      nanofabrication has surfaced as an environmentally conscious and sustainable 
      approach to manufacture antimicrobial agents that can effectively manage 
      phytopathogens. In this study, we examined the current understanding of the 
      pathogenic activities of Azadirachta indica aqueous formulated green synthesized 
      copper oxide nanoparticles (CuONPs) against phytopathogens. The CuONPs were 
      analyzed and studied using a range of analytical and microscopic techniques, such 
      as UV-visible spectrophotometer, Transmission electron microscope (TEM), Scanning 
      electron microscope (SEM), X-ray diffraction (XRD) and Fourier transformed 
      infrared spectroscopy (FTIR). The XRD spectral results revealed that the 
      particles had a high crystal size, with an average size ranging from 40 to 
      100 nm. TEM and SEM images were utilized to verify the size and shape of the 
      CuONPs, revealing that they varied between 20 and 80 nm. The existence of 
      potential functional molecules involved in the reduction of the nanoparticles was 
      confirmed by FTIR spectra and UV analysis. Biogenically synthesized CuONPs 
      revealed significantly enhanced antimicrobial activities at 100 mg/L 
      concentration in vitro by the biological method. The synthesized CuONPs at 
      500 mug/ml had a strong antioxidant activity which was examined through the free 
      radicle scavenging method. Overall results of the green synthesized CuONPs have 
      demonstrated significant synergetic effects in biological activities which can 
      play a crucial impact in plant pathology against numerous phytopathogens.
CI  - Copyright (c) 2023 Elsevier Inc. All rights reserved.
FAU - Manzoor, Muhammad Aamir
AU  - Manzoor MA
AD  - School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 
      200240, PR China.
FAU - Shah, Iftikhar Hussain
AU  - Shah IH
AD  - School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 
      200240, PR China.
FAU - Ali Sabir, Irfan
AU  - Ali Sabir I
AD  - School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 
      200240, PR China.
FAU - Ahmad, Ajaz
AU  - Ahmad A
AD  - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, 
      Riyadh 11451, Saudi Arabia.
FAU - Albasher, Gadah
AU  - Albasher G
AD  - Department of Zoology, College of Science, King Saud University, Riyadh, Saudi 
      Arabia.
FAU - Dar, Afzal Ahmed
AU  - Dar AA
AD  - Shaanxi University of Science and Technology, Xian, China.
FAU - Altaf, Muhammad Ahsan
AU  - Altaf MA
AD  - College of Horticulture, Hainan University, China. Electronic address: 
      ahsanaltaf8812@gmail.com.
FAU - Shakoor, Awais
AU  - Shakoor A
AD  - Hawkesbury Institute for the Environment, Western Sydney University, Penrith, 
      NSW, 2751, Australia. Electronic address: a.shakoor@westernsydney.edu.au.
LA  - eng
PT  - Journal Article
DEP - 20230424
PL  - Netherlands
TA  - Environ Res
JT  - Environmental research
JID - 0147621
RN  - T8BEA5064F (cuprous oxide)
RN  - 789U1901C5 (Copper)
RN  - 0 (Plant Extracts)
RN  - 0 (Oxides)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Humans
MH  - *Metal Nanoparticles/toxicity/chemistry
MH  - Copper/toxicity/chemistry
MH  - Plant Extracts/chemistry
MH  - Oxides
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Anti-Bacterial Agents/chemistry
OTO - NOTNLM
OT  - A. indica
OT  - Antioxidant
OT  - Copper oxide nanoparticles
OT  - Green synthesis
OT  - Plant pathogen
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/04/27 00:42
MHDA- 2023/06/19 13:08
CRDT- 2023/04/26 19:30
PHST- 2023/03/12 00:00 [received]
PHST- 2023/04/12 00:00 [revised]
PHST- 2023/04/17 00:00 [accepted]
PHST- 2023/06/19 13:08 [medline]
PHST- 2023/04/27 00:42 [pubmed]
PHST- 2023/04/26 19:30 [entrez]
AID - S0013-9351(23)00733-8 [pii]
AID - 10.1016/j.envres.2023.115941 [doi]
PST - ppublish
SO  - Environ Res. 2023 Aug 15;231(Pt 1):115941. doi: 10.1016/j.envres.2023.115941. 
      Epub 2023 Apr 24.