PMID- 37100710
OWN - NLM
STAT- MEDLINE
DCOM- 20230630
LR  - 20230721
IS  - 1878-3562 (Electronic)
IS  - 1590-8658 (Linking)
VI  - 55
IP  - 7
DP  - 2023 Jul
TI  - Adverse events in gastrointestinal endoscopy: Validation of the AGREE 
      classification in a real-life 5-year setting.
PG  - 933-937
LID - S1590-8658(23)00566-2 [pii]
LID - 10.1016/j.dld.2023.04.007 [doi]
AB  - BACKGROUND: The novel AGREE classification for adverse events (AEs) in 
      gastrointestinal (GI) endoscopy has not yet been validated in a real-world 
      setting. AIMS: Our study aims to evaluate the correlation between the grades of 
      AEs in the ASGE and AGREE classifications and to assess the interobserver 
      agreement of the two classification systems. METHODS: The correlation and 
      association between the AE grades of the ASGE and AGREE classifications were 
      analyzed using the Spearman rank correlation test and the chi-squared analysis, 
      respectively. A weighted Cohen's kappa coefficient analysis was performed to 
      determine the interobserver agreement of both classification systems. RESULTS: We 
      prospectively collected the AEs that occurred in our endoscopy unit over the past 
      five years. A total of 226 AEs (226/84,863, 0.3%) occurred. There was a 
      correlation between the ASGE and AGREE classifications (rho = 0.61) and a 
      moderately significant association (p < 0.01, Cramer's V = 0.7). The 
      interobserver agreement for the ASGE classification was fair (kappa 0.60, 95% 
      confidence interval [CI]: 0.54, 0.67), whereas it was good for the AGREE 
      classification (kappa 0.80, 95% CI: 0.62, 0.87). CONCLUSIONS: The AGREE 
      classification was validated for the first time in a real-world setting and 
      showed a positive correlation and higher interobserver agreement than the ASGE 
      classification.
CI  - Copyright (c) 2023 Editrice Gastroenterologica Italiana S.r.l. Published by 
      Elsevier Ltd. All rights reserved.
FAU - Crispino, Federica
AU  - Crispino F
AD  - Dipartimento di Promozione Della Salute, Materno-Infantile, di Medicina Interna e 
      Specialistica di Eccellenza (PROMISE), Gastroenterology and Hepatology Unit, 
      Piazza delle Cliniche 2, Palermo 90127, Italy; Azienda Provinciale per i Servizi 
      Sanitari (APSS), Gastroenterology and Digestive Endoscopy Unit, Santa Chiara 
      Hospital, Largo Medaglie D'Oro 9, Trento 38122, Italy.
FAU - Merola, Elettra
AU  - Merola E
AD  - Azienda Provinciale per i Servizi Sanitari (APSS), Gastroenterology and Digestive 
      Endoscopy Unit, Santa Chiara Hospital, Largo Medaglie D'Oro 9, Trento 38122, 
      Italy; Gastroenterology Unit, G.B. Grassi Hospital (ASL Roma 3), Via Gian Carlo 
      Passeroni 28, 00122 Lido di Ostia, Roma, Italy.
FAU - Tasini, Enrico
AU  - Tasini E
AD  - Azienda Provinciale per i Servizi Sanitari (APSS), Gastroenterology and Digestive 
      Endoscopy Unit, Santa Chiara Hospital, Largo Medaglie D'Oro 9, Trento 38122, 
      Italy.
FAU - Camma, Calogero
AU  - Camma C
AD  - Dipartimento di Promozione Della Salute, Materno-Infantile, di Medicina Interna e 
      Specialistica di Eccellenza (PROMISE), Gastroenterology and Hepatology Unit, 
      Piazza delle Cliniche 2, Palermo 90127, Italy.
FAU - di Marco, Vito
AU  - di Marco V
AD  - Dipartimento di Promozione Della Salute, Materno-Infantile, di Medicina Interna e 
      Specialistica di Eccellenza (PROMISE), Gastroenterology and Hepatology Unit, 
      Piazza delle Cliniche 2, Palermo 90127, Italy.
FAU - de Pretis, Giovanni
AU  - de Pretis G
AD  - Azienda Provinciale per i Servizi Sanitari (APSS), Gastroenterology and Digestive 
      Endoscopy Unit, Santa Chiara Hospital, Largo Medaglie D'Oro 9, Trento 38122, 
      Italy.
FAU - Michielan, Andrea
AU  - Michielan A
AD  - Azienda Provinciale per i Servizi Sanitari (APSS), Gastroenterology and Digestive 
      Endoscopy Unit, Santa Chiara Hospital, Largo Medaglie D'Oro 9, Trento 38122, 
      Italy. Electronic address: andrea.michielan@apss.tn.it.
LA  - eng
PT  - Journal Article
DEP - 20230424
PL  - Netherlands
TA  - Dig Liver Dis
JT  - Digestive and liver disease : official journal of the Italian Society of 
      Gastroenterology and the Italian Association for the Study of the Liver
JID - 100958385
SB  - IM
MH  - Humans
MH  - Observer Variation
MH  - *Endoscopy, Gastrointestinal/adverse effects
OTO - NOTNLM
OT  - Endoscopic mucosal resection
OT  - Endoscopic retrograde cholangiopancreatography
OT  - Endoscopic submucosal dissection
OT  - Interventional endoscopy
COIS- Declartion of Competing Interest On behalf of all authors I declare that there is 
      no conflict of interest for this manuscript.
EDAT- 2023/04/27 00:42
MHDA- 2023/06/30 06:42
CRDT- 2023/04/26 22:02
PHST- 2023/01/13 00:00 [received]
PHST- 2023/03/08 00:00 [revised]
PHST- 2023/04/09 00:00 [accepted]
PHST- 2023/06/30 06:42 [medline]
PHST- 2023/04/27 00:42 [pubmed]
PHST- 2023/04/26 22:02 [entrez]
AID - S1590-8658(23)00566-2 [pii]
AID - 10.1016/j.dld.2023.04.007 [doi]
PST - ppublish
SO  - Dig Liver Dis. 2023 Jul;55(7):933-937. doi: 10.1016/j.dld.2023.04.007. Epub 2023 
      Apr 24.