PMID- 37107928 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230430 IS - 2227-9032 (Print) IS - 2227-9032 (Electronic) IS - 2227-9032 (Linking) VI - 11 IP - 8 DP - 2023 Apr 11 TI - The Use of Cardioprotective Devices and Strategies in Patients Undergoing Percutaneous Procedures and Cardiac Surgery. LID - 10.3390/healthcare11081094 [doi] LID - 1094 AB - In the United States, about one million people are seen to visit the operating theater for cardiac surgery annually. However, nearly half of these visits result in complications such as renal, neurological, and cardiac injury of varying degrees. Historically, many mechanisms and approaches have been explored in attempts to reduce injuries associated with cardiac surgery and percutaneous procedures. Devices such as cardioplegia, mechanical circulatory support, and other methods have shown promising results in managing and preventing life-threatening cardiac-surgery-related outcomes such as heart failure and cardiogenic shock. Comparably, cardioprotective devices such as TandemHeart, Impella family devices, and venoarterial extracorporeal membrane oxygenation (VA-ECMO) have also been proven to show significant cardioprotection through mechanical support. However, their use as interventional agents in the prevention of hemodynamic changes due to cardiac surgery or percutaneous interventions has been correlated with adverse effects. This can lead to a rebound increased risk of mortality in high-risk patients who undergo cardiac surgery. Further research is necessary to delineate and stratify patients into appropriate cardioprotective device groups. Furthermore, the use of one device over another in terms of efficacy remains controversial and further research is necessary to assess device potential in different settings. Clinical research is also needed regarding novel strategies and targets, such as transcutaneous vagus stimulation and supersaturated oxygen therapy, aimed at reducing mortality among high-risk cardiac surgery patients. This review explores the recent advances regarding the use of cardioprotective devices in patients undergoing percutaneous procedures and cardiac surgery. FAU - Abdul-Rahman, Toufik AU - Abdul-Rahman T AUID- ORCID: 0000-0003-0153-287X AD - Medical Institute, Sumy State University, 40007 Sumy, Ukraine. AD - Department of Cardiology, Otto Von Guericke University of Magdeburg, 39120 Magdeburg, Germany. FAU - Lizano-Jubert, Ileana AU - Lizano-Jubert I AUID- ORCID: 0000-0002-9334-1343 AD - Centro de Investigacion en Ciencias de la Salud (CICSA), FCS, Universidad Anahuac Campus Norte, Huixquilucan 52786, Mexico. FAU - Garg, Neil AU - Garg N AD - Rowan-Virtua School of Osteopathic Medicine, One Medical Center Drive Stratford, Stratford, NJ 08084, USA. FAU - Tejerina-Marion, Emilio AU - Tejerina-Marion E AUID- ORCID: 0009-0002-7009-3102 AD - Centro de Investigacion en Ciencias de la Salud (CICSA), FCS, Universidad Anahuac Campus Norte, Huixquilucan 52786, Mexico. FAU - Awais Bukhari, Syed Muhammad AU - Awais Bukhari SM AUID- ORCID: 0000-0002-2295-1048 AD - Department of Medicine, Nishtar Medical University, Multan 60000, Pakistan. FAU - Luisa Ek, Ana AU - Luisa Ek A AUID- ORCID: 0009-0005-4589-1999 AD - Centro de Investigacion en Ciencias de la Salud (CICSA), FCS, Universidad Anahuac Campus Norte, Huixquilucan 52786, Mexico. FAU - Wireko, Andrew Awuah AU - Wireko AA AD - Medical Institute, Sumy State University, 40007 Sumy, Ukraine. AD - Department of Cardiology, Otto Von Guericke University of Magdeburg, 39120 Magdeburg, Germany. FAU - Mares, Adriana C AU - Mares AC AUID- ORCID: 0000-0003-3870-6263 AD - Division of Cardiovascular Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, USA. FAU - Sikora, Vladyslav AU - Sikora V AUID- ORCID: 0000-0002-4147-6879 AD - Medical Institute, Sumy State University, 40007 Sumy, Ukraine. AD - Department of Clinical and Experimental Medicine, University of Foggia, Via Napoli, 20, 71122 Foggia, Italy. FAU - Gupta, Rahul AU - Gupta R AUID- ORCID: 0000-0002-2511-2119 AD - Department of Cardiology, Lehigh Valley Health Network, Allentown, PA 18103, USA. LA - eng PT - Journal Article PT - Review DEP - 20230411 PL - Switzerland TA - Healthcare (Basel) JT - Healthcare (Basel, Switzerland) JID - 101666525 PMC - PMC10137626 OTO - NOTNLM OT - cardiac surgery OT - ischemia-reperfusion injury OT - ventricular assist devices COIS- The authors declare no conflict of interest. EDAT- 2023/04/28 06:41 MHDA- 2023/04/28 06:42 PMCR- 2023/04/11 CRDT- 2023/04/28 01:24 PHST- 2023/02/01 00:00 [received] PHST- 2023/02/28 00:00 [revised] PHST- 2023/04/06 00:00 [accepted] PHST- 2023/04/28 06:42 [medline] PHST- 2023/04/28 06:41 [pubmed] PHST- 2023/04/28 01:24 [entrez] PHST- 2023/04/11 00:00 [pmc-release] AID - healthcare11081094 [pii] AID - healthcare-11-01094 [pii] AID - 10.3390/healthcare11081094 [doi] PST - epublish SO - Healthcare (Basel). 2023 Apr 11;11(8):1094. doi: 10.3390/healthcare11081094.