PMID- 37111197
OWN - NLM
STAT- MEDLINE
DCOM- 20230501
LR  - 20230501
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 15
IP  - 8
DP  - 2023 Apr 20
TI  - Handgrip Strength Test and Bioelectrical Impedance Analysis in SARS-CoV-2 
      Patients Admitted to Sub-Intensive Unit.
LID - 10.3390/nu15081979 [doi]
LID - 1979
AB  - Hospitalized patients with respiratory failure due to SARS-CoV-2 pneumonia are at 
      increased risk of malnutrition and related mortality. The predictive value of the 
      Mini-Nutritional Assessment short form (MNA-sf((R))), hand-grip strength (HGS), and 
      bioelectrical impedance analysis (BIA) was determined with respect to in-hospital 
      mortality or endotracheal intubation. The study included 101 patients admitted to 
      a sub-intensive care unit from November 2021 to April 2022. The discriminative 
      capacity of MNA-sf, HGS, and body composition parameters (skeletal mass index and 
      phase angle) was assessed computing the area under the receiver operating 
      characteristic curves (AUC). Analyses were stratified by age groups (<70/70+ 
      years). The MNA-sf alone or in combination with HGS or BIA was not able to 
      reliably predict our outcome. In younger participants, HGS showed a sensitivity 
      of 0.87 and a specificity of 0.54 (AUC: 0.77). In older participants, phase angle 
      (AUC: 0.72) was the best predictor and MNA-sf in combination with HGS had an AUC 
      of 0.66. In our sample, MNA- sf alone, or in combination with HGS and BIA was not 
      useful to predict our outcome in patients with COVID-19 pneumonia. Phase angle 
      and HGS may be useful tools to predict worse outcomes in older and younger 
      patients, respectively.
FAU - Zotti, Sonia
AU  - Zotti S
AUID- ORCID: 0000-0002-5259-9831
AD  - Department of Medicine and Surgery, Internship Program in Geriatrics, Universita 
      Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy.
FAU - Luci, Isabella
AU  - Luci I
AD  - Department of Medicine and Surgery, Internship Program in Geriatrics, Universita 
      Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy.
FAU - Finamore, Panaiotis
AU  - Finamore P
AUID- ORCID: 0000-0002-8608-9223
AD  - Operative Research Unit of Internal Medicine, Fondazione Policlinico 
      Universitario Campus Bio-Medico, Via Alvaro del Portillo, 21-00128 Roma, Italy.
FAU - Travaglino, Francesco
AU  - Travaglino F
AUID- ORCID: 0000-0001-9935-0665
AD  - Operative Research Unit of Emergency Medicine, Fondazione Policlinico 
      Universitario Campus Bio-Medico, Via Alvaro del Portillo, 21-00128 Roma, Italy.
FAU - Pedone, Claudio
AU  - Pedone C
AUID- ORCID: 0000-0003-1847-9032
AD  - Department of Medicine and Surgery, Research Unit of Geriatrics, Universita 
      Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy.
AD  - Operative Research Unit of Geriatrics, Fondazione Policlinico Universitario 
      Campus Bio-Medico, Via Alvaro del Portillo, 21-00128 Roma, Italy.
FAU - Antonelli Incalzi, Raffaele
AU  - Antonelli Incalzi R
AD  - Operative Research Unit of Internal Medicine, Fondazione Policlinico 
      Universitario Campus Bio-Medico, Via Alvaro del Portillo, 21-00128 Roma, Italy.
AD  - Department of Medicine and Surgery, Research Unit of Geriatrics, Universita 
      Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy.
LA  - eng
PT  - Journal Article
DEP - 20230420
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
SB  - IM
MH  - Humans
MH  - Aged
MH  - Nutritional Status
MH  - SARS-CoV-2
MH  - Hand Strength
MH  - Electric Impedance
MH  - *COVID-19/diagnosis
MH  - *Malnutrition/diagnosis
MH  - Nutrition Assessment
MH  - Geriatric Assessment/methods
PMC - PMC10142194
OTO - NOTNLM
OT  - Mini-Nutritional Assessment
OT  - SARS-CoV-2
OT  - bioelectrical impedance analysis
OT  - hand-grip strength
OT  - in-hospital mortality
OT  - nutrition
COIS- The authors declare no conflict of interest.
EDAT- 2023/04/28 06:42
MHDA- 2023/05/01 06:42
PMCR- 2023/04/20
CRDT- 2023/04/28 01:44
PHST- 2023/03/08 00:00 [received]
PHST- 2023/03/25 00:00 [revised]
PHST- 2023/04/18 00:00 [accepted]
PHST- 2023/05/01 06:42 [medline]
PHST- 2023/04/28 06:42 [pubmed]
PHST- 2023/04/28 01:44 [entrez]
PHST- 2023/04/20 00:00 [pmc-release]
AID - nu15081979 [pii]
AID - nutrients-15-01979 [pii]
AID - 10.3390/nu15081979 [doi]
PST - epublish
SO  - Nutrients. 2023 Apr 20;15(8):1979. doi: 10.3390/nu15081979.