PMID- 37120041 OWN - NLM STAT- Publisher LR - 20231022 IS - 1526-3231 (Electronic) IS - 0749-8063 (Linking) VI - 39 IP - 11 DP - 2023 Nov TI - Cartilage Degeneration of the Lateral Compartment of the Knee at Second-Look Arthroscopy Is Associated With Deterioration of 10-Year Clinical Outcomes After Opening-Wedge High Tibial Osteotomy. PG - 2354-2362 LID - S0749-8063(23)00308-0 [pii] LID - 10.1016/j.arthro.2023.03.032 [doi] AB - PURPOSE: To identify the arthroscopic findings associated with deterioration of 10-year clinical outcomes after opening-wedge high tibial osteotomy (OWHTO) in patients with knee osteoarthritis. METHODS: A total of 114 consecutive knees of 91 patients with knee osteoarthritis who underwent OWHTO between 2007 and 2011 were retrospectively reviewed. Of these patients, those who underwent second-look arthroscopy and were followed up for a minimum of 10 years were enrolled. The Knee Society Score (KSS) and hip-knee-ankle angle were assessed. Cartilage status was graded at the time of osteotomy (first look) and plate removal (second look) according to the International Cartilage Repair Society (ICRS) grading system. The KSS knee subscale score and function subscale score were assessed separately, and on the basis of the changes in each of these scores from 1 to 10 years postoperatively and the minimal clinically important difference (MCID), the patients were divided into 2 groups: deteriorated (deterioration of score >/= MCID) and non-deteriorated (deterioration of score < MCID). RESULTS: Sixty-nine knees were included in this study. The mean knee score improved continuously from 48.7 +/- 11.3 preoperatively to 86.8 +/- 10.3 at 1 year (P < .001), 87.5 +/- 9.9 at 5 years (P < .001), and 86.5 +/- 10.5 at 10 years (P < .001) postoperatively. The mean function score also improved continuously from 62.5 +/- 12.1 preoperatively to 90.7 +/- 12.9 at 1 year (P < .001), 91.6 +/- 12.1 at 5 years (P < .001), and 88.5 +/- 13.1 at 10 years (P < .001) postoperatively. Three knees underwent conversion to total knee arthroplasty within 10 years postoperatively. The deteriorated KSS group showed significantly progressed ICRS grades in the lateral compartment compared with the non-deteriorated KSS group. The ICRS grade in the lateral compartment at second-look arthroscopy was identified as the only significant factor associated with both knee score deterioration (odds ratio, 4.89; P = .03) and function score deterioration (odds ratio, 3.91; P = .03) on multivariable logistic regression analysis. CONCLUSIONS: The presence of cartilage degeneration of the lateral compartment of the knee at second-look arthroscopy is associated with deterioration of long-term clinical outcomes after OWHTO. LEVEL OF EVIDENCE: Level IV, therapeutic case series. CI - Copyright (c) 2023 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved. FAU - Kumagai, Ken AU - Kumagai K AD - Department of Orthopaedic Surgery, Yokohama City University Hospital, Yokohama, Japan. Electronic address: kumagai@yokohama-cu.ac.jp. FAU - Yamada, Shunsuke AU - Yamada S AD - Department of Orthopaedic Surgery, Yokohama City University Hospital, Yokohama, Japan. FAU - Nejima, Shuntaro AU - Nejima S AD - Department of Orthopaedic Surgery, Yokohama City University Hospital, Yokohama, Japan. FAU - Sotozawa, Masaichi AU - Sotozawa M AD - Department of Orthopaedic Surgery, Yokohama City University Hospital, Yokohama, Japan. FAU - Inaba, Yutaka AU - Inaba Y AD - Department of Orthopaedic Surgery, Yokohama City University Hospital, Yokohama, Japan. LA - eng PT - Journal Article DEP - 20230428 PL - United States TA - Arthroscopy JT - Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association JID - 8506498 SB - IM EDAT- 2023/04/30 00:42 MHDA- 2023/04/30 00:42 CRDT- 2023/04/29 19:27 PHST- 2022/10/20 00:00 [received] PHST- 2023/03/21 00:00 [revised] PHST- 2023/03/31 00:00 [accepted] PHST- 2023/04/30 00:42 [pubmed] PHST- 2023/04/30 00:42 [medline] PHST- 2023/04/29 19:27 [entrez] AID - S0749-8063(23)00308-0 [pii] AID - 10.1016/j.arthro.2023.03.032 [doi] PST - ppublish SO - Arthroscopy. 2023 Nov;39(11):2354-2362. doi: 10.1016/j.arthro.2023.03.032. Epub 2023 Apr 28.