PMID- 37124327
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230502
IS  - 2055-2076 (Print)
IS  - 2055-2076 (Electronic)
IS  - 2055-2076 (Linking)
VI  - 9
DP  - 2023 Jan-Dec
TI  - Temporal processing deficit in children and adolescents with autism spectrum 
      disorder: An online assessment.
PG  - 20552076231171500
LID - 10.1177/20552076231171500 [doi]
LID - 20552076231171500
AB  - OBJECTIVE: The sensory deficit has been considered as one of the core features in 
      children and adolescents with autism spectrum disorder (ASD). The present study 
      aimed to examine the temporal processing of simple and more complex auditory 
      inputs in ASD children and adolescents with an online assessment that can be 
      conducted remotely. METHODS: One hundred fifty-eight children and adolescents 
      aged 5-17 years participated in this study, including 79 ASD participants and 79 
      typically developing (TD) participants. The online assessment consisted of two 
      temporal-order judgment tasks that required repeating the sequence of two pure 
      tones or consonant-vowel (CV) syllabic pairs at varying interstimulus intervals 
      (ISIs). RESULTS: Significantly lower accuracy rates were found in ASD than TD 
      participants in the pure tone and the CV conditions with both short and long ISI. 
      In addition, ASD participants (M  =  245.97 ms) showed a significantly higher 
      passing threshold than TD participants (M  =  178.84 ms) in the CV task. Receiver 
      operating characteristic analysis found that the age x ISI passing threshold 
      composite yielded a sensitivity of 74.7% and a specificity of 50.6% at the cutoff 
      point of -0.307 in differentiating ASD participants from TD participants. 
      CONCLUSION: In sum, children and adolescents with ASD showed impaired temporal 
      processing of both simple and more complex auditory stimuli, and the online 
      assessment seems to be sensitive in differentiating individuals with ASD from 
      those with TD.
CI  - (c) The Author(s) 2023.
FAU - Chan, Agnes S
AU  - Chan AS
AUID- ORCID: 0000-0002-3321-182X
AD  - Neuropsychology Laboratory, Department of Psychology, The Chinese University of 
      Hong Kong, Hong Kong, China. RINGGOLD: 26451
AD  - Research Centre for Neuropsychological Well-Being, The Chinese University of Hong 
      Kong, Hong Kong, China. RINGGOLD: 26451
FAU - Ding, Zihan
AU  - Ding Z
AUID- ORCID: 0000-0001-5921-137X
AD  - Neuropsychology Laboratory, Department of Psychology, The Chinese University of 
      Hong Kong, Hong Kong, China. RINGGOLD: 26451
FAU - Lee, Tsz-Lok
AU  - Lee TL
AUID- ORCID: 0000-0001-5993-0315
AD  - Neuropsychology Laboratory, Department of Psychology, The Chinese University of 
      Hong Kong, Hong Kong, China. RINGGOLD: 26451
FAU - Sze, Sophia L
AU  - Sze SL
AD  - Neuropsychology Laboratory, Department of Psychology, The Chinese University of 
      Hong Kong, Hong Kong, China. RINGGOLD: 26451
AD  - Research Centre for Neuropsychological Well-Being, The Chinese University of Hong 
      Kong, Hong Kong, China. RINGGOLD: 26451
FAU - Cheung, Mei-Chun
AU  - Cheung MC
AUID- ORCID: 0000-0002-0210-0772
AD  - Department of Social Work, The Chinese University of Hong Kong, Hong Kong, China. 
      RINGGOLD: 26451
LA  - eng
PT  - Journal Article
DEP - 20230424
PL  - United States
TA  - Digit Health
JT  - Digital health
JID - 101690863
PMC - PMC10134192
OTO - NOTNLM
OT  - Temporal processing
OT  - assessment
OT  - autism spectrum disorder
OT  - consonant-vowel syllable
OT  - pure tone
OT  - temporal-order judgment
COIS- The first author (ASC) received a grant from Lee Hysan Foundation. ASC is also 
      the founder and director of Pro-Talent Association Ltd. All other authors have no 
      conflict of interest to disclose.
EDAT- 2023/05/01 06:42
MHDA- 2023/05/01 06:43
PMCR- 2023/04/24
CRDT- 2023/05/01 03:41
PHST- 2022/08/11 00:00 [received]
PHST- 2023/04/06 00:00 [accepted]
PHST- 2023/05/01 06:43 [medline]
PHST- 2023/05/01 06:42 [pubmed]
PHST- 2023/05/01 03:41 [entrez]
PHST- 2023/04/24 00:00 [pmc-release]
AID - 10.1177_20552076231171500 [pii]
AID - 10.1177/20552076231171500 [doi]
PST - epublish
SO  - Digit Health. 2023 Apr 24;9:20552076231171500. doi: 10.1177/20552076231171500. 
      eCollection 2023 Jan-Dec.