PMID- 37129854 OWN - NLM STAT- Publisher LR - 20230502 IS - 1680-0745 (Electronic) IS - 1015-9657 (Linking) VI - 34 DP - 2023 Apr 28 TI - Assessment value of the modified early warning score for long-term prognosis of older patients with chronic heart failure. PG - 1-4 LID - 10.5830/CVJA-2023-003 [doi] AB - AIM: The aim of the study was to explore the assessment value of the modified early warning score (MEWS) for the long-term prognosis of older patients with chronic heart failure (CHF). METHODS: A total of 180 CHF patients, treated from January 2016 to January 2018, were divided into a grade I group (n = 28), a grade II group (n = 37), a grade III group (n = 68) and a grade IV group (n = 47) according to the New York Heart Association (NYHA) functional classification. The MEWS was compared on admission and discharge. Based on the clinical outcomes during follow up, the patients were divided into a non-survival group (n = 48) and a survival group (n = 132). Their general clinical data and the MEWS were compared. The predictive values of the MEWS, troponin I (cTnI) and B-type natriuretic (BNP) peptide for long-term prognosis were assessed using receiver operator characteristic (ROC) curves. RESULTS: The MEWS on patient discharge was significantly lower than that on admission, and it increased with increasing NYHA grade (p < 0.05). The MEWS in the non-survival group was significantly higher than that in the survival group. Different clinical outcomes were positively correlated with NYHA grade, MEWS, six-minute walking distance and left ventricular ejection fraction (r = 0.368, r = 0.471, r = 0.387, r = 0.423, p < 0.05), and negatively correlated with cTnI and BNP (r = -0.411, r = -0.425). The area under the ROC curve of the MEWS was 0.852, indicating higher accuracy. The optimal cut-off value, sensitivity and specificity of the MEWS for determining prognosis were 5.6, 0.854 and 0.797 points, respectively. CONCLUSION: The MEWS rose with increasing NYHA grade and reflected the severity of CHF in older patients, which has higher predictive value for long-term prognosis. FAU - Yin, Yin AU - Yin Y AD - Department of Cardiology, The First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region, China. Email: czk71094@163.com. FAU - Chen, Jie AU - Chen J AD - Department of Cardiology, The First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region, China. FAU - Jiang, Shijiu AU - Jiang S AD - Department of Cardiology, The First Affiliated Hospital of Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region, China. LA - eng PT - Journal Article DEP - 20230428 PL - South Africa TA - Cardiovasc J Afr JT - Cardiovascular journal of Africa JID - 101313864 SB - IM OTO - NOTNLM OT - NYHA functional classification OT - chronic heart failure OT - long-term prognosis OT - modified early warning score OT - older patient EDAT- 2023/05/02 12:43 MHDA- 2023/05/02 12:43 CRDT- 2023/05/02 11:13 PHST- 2022/11/22 00:00 [received] PHST- 2023/01/18 00:00 [accepted] PHST- 2023/05/02 12:43 [medline] PHST- 2023/05/02 12:43 [pubmed] PHST- 2023/05/02 11:13 [entrez] AID - 10.5830/CVJA-2023-003 [doi] PST - aheadofprint SO - Cardiovasc J Afr. 2023 Apr 28;34:1-4. doi: 10.5830/CVJA-2023-003.