PMID- 37132569 OWN - NLM STAT- MEDLINE DCOM- 20230504 LR - 20230508 IS - 2078-6204 (Electronic) IS - 2078-6190 (Print) IS - 2078-6190 (Linking) VI - 65 IP - 1 DP - 2023 Apr 20 TI - An introduction to insulin use in type 2 diabetes mellitus. PG - e1-e5 LID - 10.4102/safp.v65i1.5702 [doi] LID - 5702 AB - The benefits of the newer antidiabetic agents available for managing type 2 diabetes mellitus (T2DM) remain indisputable, but many patients will require insulin therapy in the disease course. Given the limited access to newer antidiabetic agents, insulin remains a standard treatment modality in T2DM in South Africa. Early, multifactorial intervention remains ideal, but glucose, blood pressure and cholesterol values remain above target in many countries. Barriers to achieving glucose control in South Africa include the healthcare provider's being unfamiliar with the practicalities of insulin administration, initiation and titration. This article highlights these gaps and offers pragmatic solutions to overcome them. FAU - Coetzee, Ankia AU - Coetzee A AD - Department of Medicine, Division of Endocrinology, Tygerberg Academic Hospital, Cape Town, South Africa; and, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town. ankiac@sun.ac.za. LA - eng PT - Journal Article DEP - 20230420 PL - South Africa TA - S Afr Fam Pract (2004) JT - South African family practice : official journal of the South African Academy of Family Practice/Primary Care JID - 9701104 RN - 0 (Hypoglycemic Agents) RN - 0 (Insulin) RN - 0 (Insulin, Regular, Human) SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2/drug therapy MH - Hypoglycemic Agents/therapeutic use MH - Insulin/therapeutic use MH - Insulin, Regular, Human MH - South Africa PMC - PMC10157446 OTO - NOTNLM OT - basal OT - insulin OT - multifactorial OT - practical OT - type 2 diabetes COIS- The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article. EDAT- 2023/05/03 12:42 MHDA- 2023/05/04 12:41 PMCR- 2023/04/20 CRDT- 2023/05/03 07:23 PHST- 2022/12/29 00:00 [received] PHST- 2023/02/28 00:00 [accepted] PHST- 2023/02/24 00:00 [revised] PHST- 2023/05/04 12:41 [medline] PHST- 2023/05/03 12:42 [pubmed] PHST- 2023/05/03 07:23 [entrez] PHST- 2023/04/20 00:00 [pmc-release] AID - SAFP-65-5702 [pii] AID - 10.4102/safp.v65i1.5702 [doi] PST - epublish SO - S Afr Fam Pract (2004). 2023 Apr 20;65(1):e1-e5. doi: 10.4102/safp.v65i1.5702.