PMID- 37133427
OWN - NLM
STAT- MEDLINE
DCOM- 20230522
LR  - 20230523
IS  - 1930-739X (Electronic)
IS  - 1930-7381 (Linking)
VI  - 31
IP  - 6
DP  - 2023 Jun
TI  - Percentage of maximum weight lost as an optimal parameter of weight regain after 
      bariatric surgery in Chinese patients with diabetes.
PG  - 1538-1546
LID - 10.1002/oby.23764 [doi]
AB  - OBJECTIVE: The goal of this study was to compare measures of weight regain (WR) 
      and their association with the glucose metabolism deterioration within 3 years 
      following bariatric surgery among Chinese patients with obesity and type 2 
      diabetes mellitus (T2DM). METHODS: Among a retrospective cohort of 249 patients 
      with obesity and T2DM who underwent bariatric surgery and were followed up to 
      3 years, WR was assessed by weight changes, BMI changes, percentage of presurgery 
      weight, percentage of nadir weight, and percentage of maximum weight lost (%MWL). 
      Glucose metabolism deterioration was defined as a change from an absence of 
      antidiabetic medication use to use, or absence of insulin use to use, or an 
      increase in glycated hemoglobin by at least 0.5% to 5.7% or greater. RESULTS: A 
      comparison of C-index of glucose metabolism deterioration indicated %MWL had 
      better discriminatory ability versus weight change, BMI change, percentage of 
      presurgery weight, or percentage of nadir weight (all p < 0.01). The %MWL also 
      had the highest prediction accuracy. The optimal %MWL cutoff point was 20%. 
      CONCLUSIONS: Among Chinese patients with obesity and T2DM who underwent bariatric 
      surgery, WR quantified as %MWL predicted 3-year postoperative glucose metabolism 
      deterioration better than the alternatives; 20% MWL was the optimal cutoff point.
CI  - (c) 2023 The Obesity Society.
FAU - Si, Yiming
AU  - Si Y
AUID- ORCID: 0000-0002-9982-4063
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
FAU - Zhang, Hongwei
AU  - Zhang H
AUID- ORCID: 0000-0003-2667-9990
AD  - Department of General Surgery, Shanghai Jiao Tong University School of Medicine 
      Affiliated Sixth People's Hospital, Shanghai, China.
FAU - Han, Xiaodong
AU  - Han X
AD  - Department of General Surgery, Shanghai Jiao Tong University School of Medicine 
      Affiliated Sixth People's Hospital, Shanghai, China.
FAU - Liu, Weijie
AU  - Liu W
AD  - Department of General Surgery, Shanghai Jiao Tong University School of Medicine 
      Affiliated Sixth People's Hospital, Shanghai, China.
FAU - Tu, Yinfang
AU  - Tu Y
AUID- ORCID: 0000-0001-8280-5213
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
FAU - Han, Junfeng
AU  - Han J
AUID- ORCID: 0000-0001-6021-229X
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
FAU - Ma, Xiaojing
AU  - Ma X
AUID- ORCID: 0000-0001-9607-161X
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
FAU - Bao, Yuqian
AU  - Bao Y
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
FAU - Yu, Haoyong
AU  - Yu H
AUID- ORCID: 0000-0002-8621-4960
AD  - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University School 
      of Medicine Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, 
      Shanghai Clinical Center of Diabetes, Shanghai Key Laboratory of Diabetes 
      Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230503
PL  - United States
TA  - Obesity (Silver Spring)
JT  - Obesity (Silver Spring, Md.)
JID - 101264860
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - *Gastric Bypass
MH  - Retrospective Studies
MH  - East Asian People
MH  - *Bariatric Surgery
MH  - Obesity/surgery/complications
MH  - Weight Gain
MH  - Glucose
MH  - *Obesity, Morbid/surgery
MH  - Treatment Outcome
EDAT- 2023/05/03 12:42
MHDA- 2023/05/22 06:42
CRDT- 2023/05/03 10:43
PHST- 2023/02/07 00:00 [revised]
PHST- 2022/04/07 00:00 [received]
PHST- 2023/02/09 00:00 [accepted]
PHST- 2023/05/22 06:42 [medline]
PHST- 2023/05/03 12:42 [pubmed]
PHST- 2023/05/03 10:43 [entrez]
AID - 10.1002/oby.23764 [doi]
PST - ppublish
SO  - Obesity (Silver Spring). 2023 Jun;31(6):1538-1546. doi: 10.1002/oby.23764. Epub 
      2023 May 3.