PMID- 37142283
OWN - NLM
STAT- MEDLINE
DCOM- 20230508
LR  - 20240521
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 16
IP  - 5
DP  - 2023 May 4
TI  - Primary pleuropulmonary synovial sarcoma presenting with recurrent spontaneous 
      pneumothorax.
LID - 10.1136/bcr-2023-254560 [doi]
LID - e254560
AB  - Primary pleuropulmonary synovial sarcoma (PPSS) is a rare mesenchymal neoplasm, 
      accounting for less than 0.5% of all primary lung tumours. Presentation is often 
      vague and may include cough, chest pain or dyspnoea. Due to the tumour's rarity, 
      diagnosis can be challenging, and not much is known about the disease process or 
      optimal treatment course. In this case report, we describe an older female 
      patient who underwent blebectomy for recurrent pneumothorax. No masses or 
      suspected lesions were found on CT imaging besides the bleb. The bleb was then 
      found to be PPSS via RT-PCR cytology. This case aims to increase awareness of 
      malignant tumours clinically presenting as recurrent pneumothorax with no 
      discrete lung mass on CT imaging. We also highlight the importance of 
      cytogenetics to confirm the diagnosis of this rare tumour.
CI  - (c) BMJ Publishing Group Limited 2023. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Do, Quan
AU  - Do Q
AD  - Internal Medicine, University of Louisville School of Medicine, Louisville, 
      Kentucky, USA quan.do@louisville.edu.
FAU - Katiyar, Vatsala
AU  - Katiyar V
AD  - Medical Oncology/Hematology, University of Louisville, Louisville, Kentucky, USA.
FAU - Rizzo, James
AU  - Rizzo J
AD  - Pathology, Baptist Health Floyd, New Albany, Indiana, USA.
FAU - Singh, Vikas
AU  - Singh V
AD  - Medical Oncology/Hematology, University of Louisville, Louisville, Kentucky, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20230504
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
SB  - IM
MH  - Humans
MH  - Female
MH  - *Pneumothorax/diagnostic imaging/etiology/surgery
MH  - *Sarcoma, Synovial/diagnosis/diagnostic imaging
MH  - Tomography, X-Ray Computed
MH  - *Lung Neoplasms/complications/diagnostic imaging/surgery
MH  - Diagnosis, Differential
PMC - PMC10163521
OTO - NOTNLM
OT  - Cancer intervention
OT  - Lung cancer (oncology)
OT  - Pathology
OT  - Pneumothorax
OT  - Radiology
COIS- Competing interests: None declared.
EDAT- 2023/05/05 00:42
MHDA- 2023/05/08 06:43
PMCR- 2025/05/04
CRDT- 2023/05/04 20:33
PHST- 2025/05/04 00:00 [pmc-release]
PHST- 2023/05/08 06:43 [medline]
PHST- 2023/05/05 00:42 [pubmed]
PHST- 2023/05/04 20:33 [entrez]
AID - 16/5/e254560 [pii]
AID - bcr-2023-254560 [pii]
AID - 10.1136/bcr-2023-254560 [doi]
PST - epublish
SO  - BMJ Case Rep. 2023 May 4;16(5):e254560. doi: 10.1136/bcr-2023-254560.